A National Cancer Institute-designated Comprehensive Cancer Center

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Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.

Why Choose City of Hope?

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

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Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

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City of Hope's institutional distinctions, breakthrough innovations and collaborations.
 


NEWS & UPDATES
  • Upon completing her final round of chemotherapy for ovarian cancer earlier this month, Maria Velazquez-McIntyre, a 51-year-old Antelope Valley resident, celebrated the milestone by giving other patients a symbol of hope – a Survivor Bell. The bell may look ordinary, but for cancer patients undergoing chemothera...
  • Many Americans understand that obesity is tied to heart disease and diabetes but, according to a new survey, too few – only 7 percent – know that obesity increases the risk of cancer. Specific biological characteristics can increase cancer risk in obese people, and multiple studies have shown correlations betwe...
  • As breast cancer survivors know, the disease’s impact lingers in ways both big and small long after treatment has ended. A new study suggests that weight gain – and a possible corresponding increase in heart disease and diabetes risk – may be part of that impact. In the first study to evaluate weight chan...
  • Becoming what’s known as an independent scientific researcher is no small task, especially when working to translate research into meaningful health outcomes. Yet that independent status is vital, enabling researchers to lead studies and avenues of inquiry that they believe to be promising. Clinicians, especial...
  • 720 days. That’s how long Alex Tung, 38, had to give up surfing after being diagnosed with acute myeloid leukemia. For most people, even some surfers, such a hiatus wouldn’t be a big deal, but for Tung, surfing has been everything. The Southern California resident began surfing when he was in elemen...
  • There are few among us who have not experienced loss of a friend or loved one, often without warning, or like those of us who care for people with cancer, after a lingering illness. It is a time when emotions run high and deep, and as time passes from the moment of loss, we often […]
  • For the past four years, neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., has been studying how breast cancer cells spread, or metastasize, to the brain, where they become life-threatening tumors. Known as secondary brain tumors, these cancers have become increasingly common as treatment advances have ena...
  • Cutaneous T cell lymphomas are types of non-Hodgkin lymphoma that arise when infection-fighting white blood cells in the lymphatic system – called lymphocytes – become malignant and affect the skin. A primary symptom is a rash that arises initially in areas of the skin that are not normally exposed to sunlight....
  • There’s science camp, and then there’s “mystery” science camp. City of Hope’s new science camp for middle school students is of the especially engaging latter variety. From Monday, July 13, to Friday, July 17, rising middle-school students from across the San Gabriel Valley were presented with a “patient” with ...
  • Women diagnosed with breast cancer quickly learn their tumor’s type, meaning the characteristics that fuel its growth. That label guides the treatment of their disease, as well as their prognosis when it comes to treatment effectiveness. Sometimes, however, doctors can’t accurately predict treatment effectivene...
  • In years past, Bladder Cancer Awareness Month has been a sobering reminder of a disease with few treatment options. For patients with metastatic disease (disease that has spread from the bladder to distant organs), average survival is typically just over one year. Fortunately, things are changing. Academic inst...
  • Tina Wang was diagnosed with Stage 4 diffuse large b cell lymphoma at age 22. She first sought treatment at her local hospital, undergoing two cycles of treatment. When the treatment failed to eradicate her cancer, she came to City of Hope. Here, Wang underwent an autologous stem cell transplant and participate...
  • When Gilbert Fresquez, 72, lost an excessive amount of weight in late 2012, he didn’t think much of it. He assumed it was a side effect from a recent surgery to remove a carcinoid tumor in his small intestine. It wasn’t until a couple of years later during a routine doctor’s visit that the retired […]
  • Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. Among both men and women, the rates of new cancers have decreased in recent years. Death rates, meanwhile, have declined among women and have held stable among men. Specialists at City of Hope are internationally r...
  • The transplant patient had been hospitalized for a couple of months. A professional violinist, he hadn’t touched his instrument for too long, ever since chemotherapy had caused his skin to peel and his fingers to go numb; they were too sensitive even to touch the metal strings, much less make them sing. He had ...