A National Cancer Institute-designated Comprehensive Cancer Center

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Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 12,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
 
Speed, efficiency and collaboration
 
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents and currently have 29 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 300 projects with institutions throughout the nation and around the world. No matter where you live, there is likely collaboration between City of Hope and a center near you.
 
Transforming the future of cancer care
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 29 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” to look at the anti-cancer properties contained within blueberries, mushrooms, cinnamon, pomegranates and grape seed extract, with the hope that they can be used to help prevent or treat cancer in a more effective way.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
 
Breakthroughs against diabetes
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
 
The philanthropic support that makes it all possible
 
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.

Why Choose City of Hope?

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 12,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
 
Speed, efficiency and collaboration
 
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents and currently have 29 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 300 projects with institutions throughout the nation and around the world. No matter where you live, there is likely collaboration between City of Hope and a center near you.
 
Transforming the future of cancer care
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 29 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” to look at the anti-cancer properties contained within blueberries, mushrooms, cinnamon, pomegranates and grape seed extract, with the hope that they can be used to help prevent or treat cancer in a more effective way.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
 
Breakthroughs against diabetes
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
 
The philanthropic support that makes it all possible
 
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

Virtual Tour of City of Hope
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Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

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City of Hope's institutional distinctions, breakthrough innovations and collaborations.
 


NEWS & UPDATES
  • The connection between lifestyle and cancer is real. Knowing that, what can individuals do to lower their risk? City of Hope physicians recently came together to answer that precise question, explaining the links between cancer and the choices we make that affect our health. Moderator Vijay Trisal M.D., medical...
  • White button mushrooms seem fairly innocuous as fungi go. Unlike portabellas, they don’t center stage at the dinner table, and unlike truffles, they’re not the subject of gourmand fervor. But appearances can be deceiving when it comes to these mild-mannered Clark Kents of the food world. In a study ...
  • Doctors often recommend preventive screenings for several cancers, based on hereditary or genetic factors, but brain tumors aren’t one of them. Primary brain tumors, which originate in the brain rather than spreading from another location, seem to develop at random, and doctors have little insight into wh...
  • Stopping cancer starts with research. To that end, STOP CANCER has awarded $525,000 in grants to City of Hope for 2015, supporting innovative research projects and recognizing the institution’s leadership in advancing cancer treatment and prevention. Founded in 1988, STOP CANCER underwrites the work of le...
  • Cancer may not be the disease many people think it is. Normally, cancer is considered to be a disease in which cells multiply at an extremely high, and unusual, rate – increasing the likelihood of genetic mutations. But increasingly, leading researchers at City of Hope and elsewhere are contending that cancer i...
  • “Of all forms of inequality, injustice in the health care system is the most shocking and inhumane.” By the time the Rev. Martin Luther King Jr. spoke those words in Chicago in 1966, the Civil Rights Act had been passed, the Voting Rights Act was the law of the land and the March on Washington was […]
  • Eight years ago, Matthew Loscalzo surprised himself by accepting the offer to become City of Hope’s administrative director of the Sheri & Les Biller Patient and Family Resource Center and executive director of the Department of Supportive Care Medicine. At the time, he was administrative director of the Sc...
  • The mental fog that patients can experience after undergoing chemotherapy treatment for cancer has a name: “chemo brain.” “Many patients report hearing or reading about chemotherapy-related cognitive deficits, but few are actually prepared to deal with these changes,” said Celina Lemon, M.A., an occupational th...
  • Cancer treatments have improved over the years, but one potential source of treatments and cures remains largely untapped: nature. Blueberries, cinnamon, xinfeng, grape seed (and skin) extract, mushrooms, barberry and pomegranates all contain compounds with the potential to treat or prevent cancer. Scientists a...
  • In the U.S., there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate and lung, according to the American Cancer Society. Each year, 5 million people are treated for skin cancer. Here, Hans Schoellhammer, M.D., assistant clinical professor at City of Hope | Ant...
  • As public health experts know, health improvement starts in the community. Now, City of Hope  has been recognized for its efforts to improve the lives of residents of its own community. The institution will receive funding from the Institute for Healthcare Improvement  to support promising community-based work ...
  • For almost four decades, blood cancer survivors who received bone marrow, or stem cell, transplants have returned to City of Hope to celebrate life, second chances and science. The first reunion, in 1976, was a small affair: spaghetti for a single patient, his brother who served as his donor and those who took ...
  • Chemotherapy is an often-essential component of cancer treatment, attacking cells that divide quickly and helping stop cancer’s advance. But the very characteristics that make chemotherapy effective against cancer also can make it toxic to healthy cells, leading to side effects such as hair loss, nausea, ...
  • When you want to understand how to enhance the patient experience, go straight to the source: The patients. Patients and their families offer unique perspectives on care and services and can provide valuable insights about what is working well and what is not. That’s why City of Hope turns to them for advice. S...
  • Take it from City of Hope researchers: Medical science isn’t just for scientists, but something the whole family can enjoy. From 1 to 4 p.m. on Saturday, May 16, the institution will offer a variety of educational and fun-filled science and healthy living activities at its second Community Science Festiva...