Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

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Breast Cancer Studies Garner $500,000 in Research Grants

September 19, 2017 | Katie Neith

Two City of Hope physicians have received yearlong grants from the Breast Cancer Research Foundation, an organization that works to prevent and cure breast cancer by advancing the world's most promising research.

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New Treatments and Personalized Care Offer Hope for Stomach Cancer Patients

January 6, 2017 | Samantha Bonar

Although it is uncommon in the U.S., stomach cancer is a serious, often devastating disease. But less than 25 percent of patients who are diagnosed with stomach cancer in the U.S. survive for five years. City of Hope’s physicians and scientists are committed to changing this.

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Don and Lois Hoffman
Breast Cancer: 'It's supposed to be a woman's disease'

June 15, 2016 | Stephanie Smith

Male breast cancer is unusual. Breast cancer being cast as “a woman’s disease” means men aren’t checking for it and therefore tend to be diagnosed later. Despite the paltry number of cases, being vigilant is important for men - a lesson Don Hoffman learned the hard way.

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Veliparib molecular formula
Biomarker linked to survival and treatment for BRCA-positive breast cancer patients

June 8, 2016 | H. Chung So

For breast cancer patients with BRCA gene mutations, compounds called poly ADP ribose (or PAR) can help determine treatment response and clinical outcomes.

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Weitzel - Increased genetic testing in young breast cancer patients
Study: Increased genetic testing in young breast cancer patients

February 16, 2016 | Valerie Howard

More young breast cancer patients are relying on genetic testing to make informed surgical decisions. According to a new study, published online in JAMA Oncology, nearly all women under 40 years old surveyed in 2013, had undergone BRCA testing within a year of a breast cancer diagnosis, with the vast majority of those who tested positive opting for a double-mastectomy.

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Is genetic testing for cancer risk right for you? What you need to know

January 28, 2016 | Travis Marshall

Cancer researchers, like those at City of Hope, have come to understand that mutations in certain genes can mean a higher likelihood of getting certain types of cancer. That’s why genetic testing to identify these mutations has become an important tool in figuring out people’s risk of getting cancer in their lifetimes.

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Breakthroughs - genetic testing
Breast cancer survivor urges young women to consider genetic testing

December 22, 2015 | Valerie Howard

Young women can feel as if they’re invincible, with no need to worry about something as remote as cancer – and certainly no need to worry about how their family members’ health might affect their own. Nothing could be further from the truth, especially for women of Hispanic and African American descent. Women of those ethnic backgrounds are more likely than other women to die from cancer.

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breast cancer
ASCO 2015: Clinical trial assesses options for triple-negative breast cancer

May 28, 2015 | Nicole Levine

A clinical trial currently being conducted at City of Hope and elsewhere suggests that researchers are developing improved treatment options for young women with advanced triple-negative breast cancer, a particularly difficult-to-treat disease.

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genetic testing
Discovering tools for genetic testing – and teaching others to use them

March 22, 2015 | Nicole White

The understanding of the relationship between genetics and cancer risk continues to grow, with more genetic testing than ever before available to patients. City of Hope leaders have created a program to teach clinicians nationwide and worldwide how to use available genetic testing tools.

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BRCA gene mutations
New screening panel could target BRCA mutations common to Hispanic women

February 18, 2015 | Nicole White

Although many Hispanic women face a high risk of mutations in the BRCA1 and BRCA2 genes – increasing their risk of breast and ovarian cancer – screenings for these mutations can be prohibitively expensive in Mexico and other Latin American countries.

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