City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
June 15, 2016 | Stephanie Smith
Male breast cancer is unusual. Breast cancer being cast as “a woman’s disease” means men aren’t checking for it and therefore tend to be diagnosed later. Despite the paltry number of cases, being vigilant is important for men - a lesson Don Hoffman learned the hard way.
June 8, 2016 | H. Chung So
For breast cancer patients with BRCA gene mutations, compounds called poly ADP ribose (or PAR) can help determine treatment response and clinical outcomes.
January 5, 2015 | Nicole White
Betsy Sauer and her four daughters share plenty in common. They’re smart and successful. They’re funny, ranging from wryly witty to wickedly hilarious. Their hobbies tend toward the active and adventurous: hiking, rock climbing, skiing, swimming, fishing, kayaking, yoga and horseback riding.
November 21, 2014 | Valerie Zapanta
When it comes to cancer, your family history may provide more questions than answers: How do my genes increase my risk for cancer? No one in my family has had cancer; does that mean I won’t get cancer? What cancers are common in certain populations and ethnicities? City of Hope experts have some guidance.
October 27, 2014 | Valerie Zapanta
Genetics, genes, genome, genetic risk ... Such terms are becoming increasingly familiar to even nonresearchers as studies and information about the human make-up become more extensive and more critical.
October 14, 2014 | Nicole White
The leading risk factor for breast cancer is simply being a woman. The second top risk factor is getting older. Many breast cancer risk factors, such as gender and aging, cannot be controlled. But lacing up for a walk a few times a week can put a dent in breast cancer risk.
May 26, 2014 | Hiu Chung So
For patients with BRCA mutation-associated breast cancer, the experimental drug ABT-888 — also known as veliparib — is showing promise as a treatment, according to phase II clinical trial results that will be reported at the upcoming annual meeting of the American Society of Clinical Oncology.
October 28, 2013 | Tami Dennis
"How far would you go to save your life?" That's the question faced by women who find they're carriers of the BRCA genetic mutations, which dramatically increase their risk of breast and ovarian cancer.
October 2, 2013 | Nicole White
Most breast cancers are not genetic, but for women who carry a BRCA mutation, their risk of developing breast cancer can be as high as 85 percent over their lifetime. City of Hope researchers received $380,000 to study breast cancer mutations that affect Latinas.
June 17, 2013 | Hiu Chung So
Months after hearing the arguments and weeks before concluding its current session, the Supreme Court unanimously ruled that human genes are a product of nature and are not patentable. On June 13, the Supreme Court ruled that human genes are not patentable, thus allowing other companies to test for BRCA gene mutations at a fraction of the current price.