Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

breakthroughs - Behnam Badie and Christine Brown
$12.8 Million CIRM Grant Awarded to City of Hope for CAR-T Cell Brain Cancer Research

October 16, 2017 | Michael Easterling

Christine Brown, Ph.D., and Behnam Badie, M.D., have received a $12.8 million grant from the California Institute for Regenerative Medicine (CIRM) to fund their work using CAR-T cells to combat brain cancer.

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City of Hope Neurosurgeon, Behnam Badie, M.D.
Patient and Pioneer Richard Grady: His Contributions to Advance Our Research in Treating Brain Tumors Is His Lasting Legacy

August 2, 2017 | Behnam Badie, M.D., F.A.C.S.

My life is devoted to finding a cure for brain cancer. Patients come to us seeking miracles, but often what they give us back is invaluable knowledge. Throughout history, patients have helped revolutionize science and medicine. Many patients, like my dad, do not survive. But they leave behind a legacy of knowledge and hope for other patients today, and for future generations. Richard Grady was that kind of patient.

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Behnam Badie in Surgery
MEET OUR DOCTORS: Behnam Badie on why ‘being a neurosurgeon is not enough’

July 17, 2017 | Denise Heady

Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's. 

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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breakthroughs - behnam badie
Behnam Badie awarded $2.1 million R01 grant to help patients with aggressive brain tumors

April 24, 2017 | Denise Heady

What started as an unplanned lunch date has turned into a potential breakthrough in the treatment of gliomas – a fast-growing, and often deadly type of brain tumor.

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CIRM Annual Symposium of the Alpha Stem Cell Clinics Network
CIRM Symposium: New Developments in Stem Cell Therapies

March 28, 2017 | Michael Easterling

The stories of patients who have benefited from stem cell therapies funded by the California Institute for Regenerative Medicine (CIRM) were the focus of the second symposium of the institute’s Alpha Stem Cell Clinics Network.

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breakthroughs- world cancer day
World Cancer Day: New treatments and cures start with collaborations

February 3, 2017 | Denise Heady

Defeating cancer cannot be done alone. It requires a team approach. Here are just a few examples of how City of Hope scientists and physicians are working together to create leading-edge approaches to end cancer.

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breakthroughs - t cells
INSIDE THE LAB: Tracking T cells in the brain

January 27, 2017 | Denise Heady

City of Hope researchers have seen initial success treating brain cancer patients with CAR-T cell therapy, yet questions still linger about what exactly happens to these cells once they disperse through the brain. A new imaging technique may be the answer.

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Inside CAR T 256 x 256
Inside CAR-T Cell Brain Surgery

January 4, 2017 | Stephanie Smith

Sketches of a brain surgery performed on B., one of several patients in a breakthrough clinical trial for brain cancer at City of Hope. Early results of the trial — describing promising results using CAR-T cells for a 50-year-old patient with an aggressive brain cancer called glioblastoma multiforme — were published recently in the New England Journal of Medicine.

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