Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

CAR T Illuminated
City of Hope Will Offer First FDA-approved CAR-T Cell Therapy for Patients with Some Types of Lymphoma

October 18, 2017 | City of Hope

City of Hope will be the one of the first authorized centers in the nation to provide axicabtagene ciloleucel, which the U.S. Food and Drug Administration (FDA) announced today is the first approved CAR-T therapy for adult patients who have not responded to or who have relapsed after at least two other kinds of treatment.

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breakthroughs - Behnam Badie and Christine Brown
$12.8 Million CIRM Grant Awarded to City of Hope for CAR-T Cell Brain Cancer Research

October 16, 2017 | Michael Easterling

Christine Brown, Ph.D., and Behnam Badie, M.D., have received a $12.8 million grant from the California Institute for Regenerative Medicine (CIRM) to fund their work using CAR-T cells to combat brain cancer.

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Leo Wang 1 - HHOW
Leo Wang awarded grant to help support CAR-T cell therapy research for pediatric brain tumors

September 15, 2017 | Denise Heady

To help further City of Hope’s research in CAR-T therapy, Leo Wang, M.D., Ph.D., a dual-trained pediatric oncologist and scientist, was awarded with a Hyundai Young Investigator Grant funded by the Hyundai Hope On Wheels program.

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City of Hope Neurosurgeon, Behnam Badie, M.D.
Patient and Pioneer Richard Grady: His Contributions to Advance Our Research in Treating Brain Tumors Is His Lasting Legacy

August 2, 2017 | Behnam Badie, M.D., F.A.C.S.

My life is devoted to finding a cure for brain cancer. Patients come to us seeking miracles, but often what they give us back is invaluable knowledge. Throughout history, patients have helped revolutionize science and medicine. Many patients, like my dad, do not survive. But they leave behind a legacy of knowledge and hope for other patients today, and for future generations. Richard Grady was that kind of patient.

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Breakthroughs - brain tumors and cancer - what you need to know - 256x256
Brain tumors and cancer: what you need to know

July 18, 2017 | Denise Heady

Say the words “brain tumor” and most people will likely think of cancer. But there’s reason for optimism - recent advances in screening and treatment, such as CAR-T cell therapy, mean patient outcomes and quality of life are continuing to improve.

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Behnam Badie in Surgery
MEET OUR DOCTORS: Behnam Badie on why ‘being a neurosurgeon is not enough’

July 17, 2017 | Denise Heady

Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's. 

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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