Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Defu Zeng City of Hope
New Clues Could Point to Better Treatments for Chronic Graft-Versus-Host Disease (GVHD)

November 9, 2017 | By Katie Neith

City of Hope’s Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation and colleagues recently uncovered important information about the chronic GVHD.

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Novel Treatment May Stop Graft-Versus-Host Disease

April 18, 2017 | Katie Neith

An international team of researchers led by City of Hope’s Defu Zeng believe they may have found a way to prevent graft-versus host disease following stem cell transplants without sacrificing the transplants’ ability to fight leukemia and lymphoma.

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Type 1 Diabetes: A Primer

January 24, 2017 | Samantha Bonar

Type 1 diabetes is an autoimmune disorder in which the body’s immune system attacks and destroys the insulin-producing beta cells of the pancreas. Here's a look at the past, present and future of this disease.

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$2.2 million grant will benefit graft-versus-host disease research

November 20, 2015 | City of Hope

Graft-versus-host disease is a serious condition that affects many people who receive a bone marrow cell transplant. To better fight it, scientists need to better understand it. City of Hope researchers’ efforts to do just that recently got a $2.2 million boost from the National Institute of Allergy and Infectious Diseases, also known as NIAID.

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She lost brother to graft-versus-host disease; now she fights back

August 9, 2013 | Nicole White

Rosie Mae Henson is continuing a fight she feels her brother John should have won. John successfully conquered his cancer with a bone marrow transplant, but died a year later from graft-versus-host disease in which the new donor cells attack the transplant recipient’s body.

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Graft-versus-host disease: Answers for bone marrow transplantation

June 14, 2013 | Darrin Joy

Patients struggling to overcome blood cancers face a wider threat than just the malignant cells menacing their bodies. They also face challenging — even life-threatening — treatment side effects. For many patients undergoing bone marrow transplantation, graft-versus-host disease (GVHD) ranks as one of the most dangerous.

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Can donated marrow do away with type 1 diabetes?

June 21, 2012 | City of Hope Staff

City of Hope researchers are working on a treatment for type 1 diabetes that could potentially cure the disease without toxic side effects. Defu Zeng and his team published the latest results from their lab studies in Science Translational Medicine on May 9.

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