March 13, 2018 | Denise Heady
Fourteen years ago, neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., began to travel to underserved countries to perform brain surgeries on disadvantaged children.
Targeting a cancer cell’s “master switch”
May 9, 2016 | City of Hope
According to a new study published in the prestigious scientific journal, Immunity, scientists at City of Hope have unlocked a key component of STAT3 activation, a gene that has long been associated with tumor cell growth and antitumor immune suppression. By exploring how STAT3 is activated in B cells, a major type of immune cell, our researchers have identified a novel target for cancer therapy.
International women’s day: 7 women changing the world of cancer treatment
March 8, 2016 | City of Hope
At City of Hope, we’re proud to have some of the most talented and passionate women in the medical industry serving at every level of the organization. Here, we’ve spotlighted just a few of the many City of Hope physicians and scientists who are breaking exciting new ground in cancer research, treatment and care.
Antibodies discovery could revolutionize the treatment of cancer
February 2, 2016 | Elise Lamar
Stat, Myc, Myb, Fos, Ras, and Fox: Those bland monosyllables, unfamiliar to most of us, command the respect and fear of oncologists and cancer researchers worldwide. Why? Because they name proteins that drive uncontrollable cell division, metastasis, and/or drug resistance in numerous cancers.
Made in City of Hope: Drug stops cancer’s siren call to the immune system
December 4, 2014 | City of Hope
Cancer has a way of “talking” to the immune system and corrupting it to work on its own behalf instead of defending the body. Blocking this communication would allow the immune system to see cancer cells for what they are – something to be fought off – and stop them from growing.
Cancer researcher's work on STAT3 protein gets international recognition
October 4, 2014 | Darrin Joy
Cancer cells are masters of survival. Despite excessive damage to their most basic workings and the constant vigilance of the body’s immune system, they manage to persevere. Hua Yu was recently awarded with the prestigious Humboldt Research Award for her numerous breakthrough discoveries involving STAT3 .
Diabetes research: From epigenetics to islet cell transplants
January 4, 2014 | Elizabeth Stewart
Nearly 350 million people worldwide are coping with diabetes, and the disease is expected to be the seventh-leading cause of death by 2030. Aware of these grim statistics, researchers at City of Hope are committed to halting the global epidemic.
Lung cancer: 7 breakthroughs in research, treatment, diagnosis
October 30, 2013 | C. Kitchens
Lung cancer is not unbeatable. Each day, doctors and researchers in City of Hope’s Lung Cancer and Thoracic Oncology Program aggressively pursue innovative approaches to bring new treatments and cures to patients with all forms of this devastating disease.
Cancer: Advances in immunotherapy bring victory closer
August 20, 2013 | Rachel Hall
Immunotherapy is no longer a treatment of the future. At City of Hope, researchers are now advancing immunotherapy as an approach to treat and cure devastating illnesses — conducting innovative research in the laboratory, even while improving lifesaving standard treatments in the clinic.
'Microenvironement' of lung cancer offers clues to survival
May 25, 2013 | Nicole White
In an effort to predict, treat and cure disease, scientists are exploring the smaller ecosystems that exist within the body. The tumor microenvironment – the site and surroundings where tumor cells grow – can hold important clues to help predict which cancer patients are at highest risk of their cancer spreading.