Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Breakthroughs - targeting cancer cell master switch
Targeting a cancer cell’s “master switch”

May 9, 2016 | City of Hope

According to a new study published in the prestigious scientific journal, Immunity, scientists at City of Hope have unlocked a key component of STAT3 activation, a gene that has long been associated with tumor cell growth and antitumor immune suppression. By exploring how STAT3 is activated in B cells, a major type of immune cell, our researchers have identified a novel target for cancer therapy.

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Breakthroughs - targeting cancer cell master switch
The role of B cells to target cancer's master switch

May 9, 2016 | City of Hope

In a study published in Immunity, scientists have unlocked a key component of STAT3 activation, a gene that has long been associated with tumor cell growth and anti-tumor immune suppression.

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International womens day
International women’s day: 7 women changing the world of cancer treatment

March 8, 2016 | City of Hope

At City of Hope, we’re proud to have some of the most talented and passionate women in the medical industry serving at every level of the organization. Here, we’ve spotlighted just a few of the many City of Hope physicians and scientists who are breaking exciting new ground in cancer research, treatment and care.

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Breakthroughs - antibodies discovery could change cancer treatment - 256x256
Antibodies discovery could revolutionize the treatment of cancer

February 2, 2016 | Elise Lamar

Stat, Myc, Myb, Fos, Ras, and Fox: Those bland monosyllables, unfamiliar to most of us, command the respect and fear of oncologists and cancer researchers worldwide. Why? Because they name proteins that drive uncontrollable cell division, metastasis, and/or drug resistance in numerous cancers.

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COH_5932
Made in City of Hope: Drug stops cancer’s siren call to the immune system

December 4, 2014 | City of Hope

Cancer has a way of “talking” to the immune system and corrupting it to work on its own behalf instead of defending the body. Blocking this communication would allow the immune system to see cancer cells for what they are – something to be fought off – and stop them from growing.

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Hua Yu
Cancer researcher's work on STAT3 protein gets international recognition

October 4, 2014 | Darrin Joy

Cancer cells are masters of survival. Despite excessive damage to their most basic workings and the constant vigilance of the body’s immune system, they manage to persevere. Hua Yu was recently awarded with the prestigious Humboldt Research Award for her numerous breakthrough discoveries involving  STAT3 .

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lung cancer
Lung cancer: 7 breakthroughs in research, treatment, diagnosis

October 30, 2013 | C. Kitchens

Lung cancer is not unbeatable. Each day, doctors and researchers in City of Hope’s Lung Cancer and Thoracic Oncology Program aggressively pursue innovative approaches to bring new treatments and cures to patients with all forms of this devastating disease.

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Cancer: Advances in immunotherapy bring victory closer

August 20, 2013 | Rachel Hall

Immunotherapy is no longer a treatment of the future. At City of Hope, researchers are now advancing immunotherapy as an approach to treat and cure devastating illnesses — conducting innovative research in the laboratory, even while improving lifesaving standard treatments in the clinic.

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