Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Russell Rockne
Youth Movement: Donor generosity supports talented junior investigators

February 3, 2017 | City of Hope

On World Cancer Day, we celebrate the donor support that is such a critical part of the quest to cure cancer, enabling City of Hope physicians and scientists to develop their discoveries and translate them into cures for patients.

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Circle 1500 funds womens cancers research projects with pooled membership dues

October 22, 2015 | Kelly Mayfield

Circle 1500 — a giving circle made up of patients, community members, friends and families of women affected by cancer — meets every quarter to pool resources and funds to support breakthroughs for women's cancers at City of Hope.

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brain tumor program
Unsatisfied with today's therapies, brain tumor scientists make new ones

June 8, 2015 | David Levine

Clinicians and surgeons at City of Hope aren’t satisfied with current treatments for brain tumors, nor are they satisfied with focusing on only one avenue of research. Instead, they’re exploring many potential – and promising – options to help people with cancer in the brain.

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Carbon Nanotube_Animation
Destroying brain tumors with nanoparticles

January 29, 2015 | Hiu Chung So

Despite advances in surgery, radiation and drug therapy, brain tumors remain particularly challenging to treat. This is due to the tumor’s location, which can limit localized therapies’ effectiveness, and the blood-brain barrier , which blocks many cancer-fighting drugs’ passage from the bloodstream to the tumor site.

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Blood test
What makes City of Hope research different? Collaboration (w/VIDEO)

May 8, 2014 | Tami Dennis

Regardless of their institution, all cancer researchers want one thing – to find a cure for cancer. But City of Hope researchers have some advantages in this quest. The advantages start with a culture of collaboration.

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To fight cancer, nanoparticles need a better disguise

May 22, 2013 | Nicole White

In  the search for better ways to deliver powerful chemotherapy drugs only to tumors, leaving healthy tissue unscathed, nanoparticles are emerging as a promising tool. These tiny particles can be loaded with powerful chemotherapy drugs that, ideally, can be delivered directly to the cancer site.

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Tiny gold rods could be used to attack hard-to-reach cancers

May 16, 2013 | Nicole White

Gold  has been used for jewelry, to fill teeth and to garnish desserts. Now, the precious metal  may also prove to be an important tool for fighting cancer. Gold nanoparticles, exponentially smaller than these more traditional nuggets, could be embedded in neural stem cells and used in targeted cancer therapies, suggests research conducted at City of Hope.

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E. coli
Nanomagnets could combat drug-resistant bacteria, researcher says

May 14, 2013 | Tami Dennis

Drug-resistant bacteria have made headline after headline, created problem after problem. And yet, they're still with us. One City of Hope researcher has a provocative aim, however: To remove multidrug resistant bacteria from our blood using nanomagnets as "nanobiotics.

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Using neural stem cells to sneak up on breast cancer metastases

May 3, 2013 | Nicole White

A City of Hope researcher has been awarded a grant to use neural stem cells, which naturally home in on cancer cells (shown here), to deliver cancer-fighting drugs. Triple-negative breast cancer is both aggressive and tough to fight with existing therapies, a combination that often results in the disease's spread; in fact, most deaths related to this form of cancer occur due to metastases.

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