Prostate cancer advances help extend a patient's life

September 11, 2018 | Dory Benford

Johnny Lopez's research into the latest prostate cancer treatments, clinical trials, experimental therapies — anything to avoid chemotherapy, and a recommendation from a friend also battling prostate cancer, led him to Tanya Dorff, M.D., and City of Hope.

Continue Reading

First-of-its-kind CAR T clinical trial enrolls HER2+ breast cancer patients with brain metastases

October 30, 2018 | City of Hope

City of Hope is now enrolling patients in a phase 1 trial evaluating the safety and efficacy of CAR T cell therapy in patients with HER2+ breast cancer that has metastasized to the brain.

Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain

October 30, 2018 | Letisia Marquez

A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants. 

CIRM Awards City of Hope Researchers $3.7 million to Develop Glioblastoma Clinical Trial

September 28, 2018 | Letisia Marquez

California Institute for Regenerative Medicine has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients, which would genetically alter blood stem cells to better tolerate chemotherapy.

City of Hope Awarded $3.7 million to Develop Glioblastoma Clinical Trial

June 29, 2018 | Letisia Marquez

California Institute for Regenerative Medicine has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients, which would genetically alter blood stem cells to better tolerate chemotherapy.

Brain tumor patient is first person treated in new stem cell clinic

July 7, 2015 | City of Hope

A gliobastoma patient has become the first person to be treated by City of Hope's new Alpha Clinic for Cell Therapy and Innovation (ACT-I), heralding a potential breakthrough in the treatment for brain tumors and in the use of stem cells.

Brain tumor expert Jana Portnow: 'I want to help ... as much as I can'

June 17, 2015 | David Levine

Jana Portnow , M.D., associate director of the Brain Tumor Program at City of Hope, didn’t expect to specialize in treating brain tumors. But, early in her career, she undertook a year of research on pain management and palliative care and, in that program, got to know many patients with brain tumors.

Unsatisfied with today's therapies, brain tumor scientists make new ones

June 8, 2015 | David Levine

Clinicians and surgeons at City of Hope aren’t satisfied with current treatments for brain tumors, nor are they satisfied with focusing on only one avenue of research. Instead, they’re exploring many potential – and promising – options to help people with cancer in the brain.

The future is here: $8 million CIRM grant will launch stem cell clinic

November 16, 2014 | Nicole White

Identifying cures for currently incurable diseases and providing patients with safe, fast and potentially lifesaving treatments is the focus of City of Hope’s new Alpha Clinic for Cell Therapy and Innovation (ACT-I).

Made in City of Hope: Neural stem cells could stop brain tumor recurrence

October 31, 2014 | City of Hope

Brain tumors are exceptionally difficult to treat. They can be removed surgically, but individual cancer cells may have already spread elsewhere in the brain and can escape the effects of both radiation and chemotherapy.