Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Cardiovascular disease is linked to mysterious genetic material

August 26, 2013 | Darrin Joy

Cardiovascular disease — often stemming from common conditions such as diabetes, hypertension, atherosclerosis and kidney failure — claims about 600,000 U.S. lives each year. It’s the nation’s leading cause of death.

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Immunotherapy enlists more than just T cells to treat leukemia

April 10, 2013 | Shawn Le

Most cancer immunotherapies are designed to take a patient’s own T cells, a type of white blood cell, and genetically engineer them to target, and destroy, cancer cells. But T cells are only one part of the immune response, and eliciting an effective response from an immune system already weakened by cancer can be difficult – especially in leukemia, in which defective white blood cells are the problem.

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Gene therapy targets metastasis to stop breast cancer

April 8, 2013 | Shawn Le

Breast cancer remains the leading cancer diagnosis in women and, overall, the second-leading cause of cancer-related deaths in the U.S. The American Cancer Society reports that the five-year survival rate for women whose breast cancers are diagnosed at an early stage — when the cancer cells are still localized — is 98 percent.

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Nick Snead_Flippin biomaterials figure with citation
Flippin' Biomaterials

April 1, 2013 | Nick Snead

I saw this paper published in  Science , authored by (as one of my undergraduate biomedical engineering biomaterials professors put it) one of the "demigods" of biomaterials, Bob Langer, and an up-and-coming materials scientist named Dan Anderson, who is making lots of siRNA-delivery biomaterials, too.

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On World AIDS Day, scientific advances elicit optimism

December 1, 2012 | Shawn Le

World AIDS Day is marked this year with a renewed optimism that science and medicine could soon change the course of the disease -- again. First came the AIDS drug AZT , then the combinations of antiretroviral drugs known as AIDS cocktails .

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Nick Snead
Attending scientific conferences saves me time

April 2, 2012 | Nick Snead

I am very humbled and feel blessed every time I am given the opportunity to attend a science conference. I was at my previous institution when I went to my first “real” science conference in the summer of 2008.

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Nick Snead
How I came to City of Hope: the transition from engineering to biology

March 6, 2012 | Nick Snead

I often joke that, when I was studying biomedical engineering, we were only encouraged to learn the bare minimum of the biology that we needed to know in order to do our project. It was, however, partly true.

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Krist T. Azizian
Blood stem cells - evolving compensation

March 5, 2012 | Krist Azizian

Disrupting a critical molecular pathway for blood development reveals biology’s robustness. Some faint at the sight of it. Others relish seeing it splattered gratuitously in vampire movies. Blood, with all its symbolism, has intrigued mankind for millennia.

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