Prostate cancer advances help extend a patient's life

September 11, 2018 | Dory Benford

Johnny Lopez's research into the latest prostate cancer treatments, clinical trials, experimental therapies — anything to avoid chemotherapy, and a recommendation from a friend also battling prostate cancer, led him to Tanya Dorff, M.D., and City of Hope.

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First-of-its-kind CAR T clinical trial enrolls HER2+ breast cancer patients with brain metastases

October 30, 2018 | City of Hope

City of Hope is now enrolling patients in a phase 1 trial evaluating the safety and efficacy of CAR T cell therapy in patients with HER2+ breast cancer that has metastasized to the brain.

Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain

October 30, 2018 | Letisia Marquez

A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants. 

Parker Institute for Cancer Immunotherapy Welcomes Stephen J. Forman, M.D.

September 27, 2018 | Letisia Marquez

City of Hope’s Stephen J. Forman, M.D., is now an official member of the Parker Institute for Cancer Immunotherapy.

CAR T researcher Saul Priceman wants to teach your body to fight cancer

September 13, 2018 | Letisia Marquez

Since 2013, City of Hope researcher Saul Priceman, Ph.D., and his team have developed one of most comprehensive CAR T programs in the nation.

City of Hope's Stephen J. Forman Joins Parker Institute for Cancer Immunotherapy

July 16, 2018 | Letisia Marquez

City of Hope’s CAR T research and treatment team is now an official member of the Parker Institute for Cancer Immunotherapy.

CAR T Laboratory Research Yields Promising Prostate Cancer Results

April 17, 2018 | Letisia Marquez

City of Hope physicians have successfully treated blood cancers with chimeric antigen receptor (CAR) T cell therapy, and they are working to expand that therapy to patients with prostate cancer and other solid tumors.

With New CAR T Approach, City of Hope CEACAM Research Comes Full Circle

February 9, 2018 | Jyoti Madhusoodanan

CEA remains one of the most widely used clinical markers of cancer. As the diverse roles of CEA and CEACAMs, have grown clearer, researchers at City of Hope are working on a new wave of clinical tools and therapies.

Scientists uncover important step in tumors' blocking of immune system

March 19, 2014 | Nicole White

Cancers thrive and spread in part because of their ability to create fortresses around themselves that ward off the body’s natural immune defenses, a so-called immunosuppressive microenvironment.  A new study sheds light on how a tumor is able to work against the body's immune system, a discovery with the potential to unlock new immunotherapies.