June 25, 2018 | Katie Neith
In an effort to improve options for those with liver cancer, a group of researchers have identified a way of potentially treating a broad range of liver diseases and perhaps even other types of cancer.
Collaboration leads to new pathway to increase drug sensitivity
October 19, 2016 | Katie Neith
Science doesn’t always start in the lab. Sometimes collaborations come together over cocktails in Costa Rica. This is how City of Hope cancer biologist Mei Kong Ph.D., and Caltech neuroscientist Viviana Gradinaru, Ph.D., started a project that could change the approach to killing cancerous tumors.
What makes City of Hope research different? Collaboration (w/VIDEO)
May 8, 2014 | Tami Dennis
Regardless of their institution, all cancer researchers want one thing – to find a cure for cancer. But City of Hope researchers have some advantages in this quest. The advantages start with a culture of collaboration.
Women's cancers: Discoveries start with basic research
March 16, 2014 | Elizabeth Stewart
At City of Hope, we're committed to caring for the whole person. This mission is especially important when it comes to treating women, who devote so much of their time and energy to caring for others — for their families, friends and communities.
Antidepressant Paxil boosts estrogen activity, new study finds
February 18, 2014 | Hiu Chung So
Humans are exposed to countless chemicals every day, so identifying the ones that can impact their health – specifically the ones that can increase cancer risk – is akin to looking for a sugar crystal in a salt shaker.
Brain tumor research: 3 foundations back neural stem cell work
February 18, 2014 | Hiu Chung So
Despite gradual improvements over the years, brain tumors remain particularly tricky to treat. Treatment can affect normal brain tissue, which can cause physical and cognitive impairment. One particularly challenging obstacle is the blood-brain barrier, which prevents cancer drugs from passing into the brain and attacking the tumor.
New CMV vaccine targets virus affecting third of transplant patients
February 2, 2014 | Nicole White
In most healthy adults, the immune system wages a winning battle against a virus that infects up to 80 percent of the population by age 40. Most never even know they have cytomegalovirus, or CMV. John Zaia, chair of the Department of Virology, checks on Jasson Duran, the first volunteer enrolled in a study of a new CMV vaccine developed and manufactured at City of Hope.
Veliparib shows promise for BRCA-related breast cancer patients
January 9, 2014 | City of Hope
Of the estimated 230,000 new cases of breast cancer diagnosed annually in the U.S., approximately 12,000 patients carry harmful mutations on either the BRCA1 or BRCA2 genes. Researchers are investigating the effectiveness of various drugs against breast cancer, including the PARP inhibitor veliparib.
Breast cancer spreads to brain by masquerading as neurons, study finds
January 9, 2014 | Nicole White
Often, several years can pass between the time a breast cancer patient successfully goes into remission and a related brain tumor develops. During that time, the breast cancer cells somehow hide, escaping detection as they grow and develop.
Diabetes: Discovery could make growing islet cells easier
October 22, 2013 | Nicole White
Transplantation of insulin-producing islet cells is a potentially powerful tool for treating type 1 diabetes, but coming up with enough healthy donor cells for the procedure is difficult – at least for now.
Chinese medicine compound could block liver cancer
October 18, 2013 | Darrin Joy
Liver cancer is tough to treat, and it’s on the rise. Now among the top 10 cancers diagnosed in the U.S. each year, it’s the third-deadliest cancer in the world. But a compound found in a traditional Chinese medicine may one day help halt the disease’s advance.