City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
November 1, 2017 | Denise Heady
Say the words “brain tumor” and most people will likely think of cancer. But there’s reason for optimism - recent advances in screening and treatment, such as CAR-T cell therapy, mean patient outcomes and quality of life are continuing to improve.
July 24, 2017 | Denise Heady
A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.
July 17, 2017 | Denise Heady
Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's.
July 17, 2017 | Denise Heady
City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
July 10, 2017 | Stephanie Smith
T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.
June 5, 2017 | Rahul Jandial, M.D., Ph.D.
In the past seven years at City of Hope, I’ve had the privilege of providing care for many patients with cancer. Quite simply, they are the real superhumans. Please allow me to offer four examples for your consideration, from my personal insight.
January 30, 2017 | City of Hope
A study led by scientists at the Translational Genomics Research Institute (TGen), a City of Hope affiliate, has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer.
January 4, 2017 | Stephanie Smith
Sketches of a brain surgery performed on B., one of several patients in a breakthrough clinical trial for brain cancer at City of Hope. Early results of the trial — describing promising results using CAR-T cells for a 50-year-old patient with an aggressive brain cancer called glioblastoma multiforme — were published recently in the New England Journal of Medicine.
September 27, 2016 | Veronique de Turenne
When Nick Troftgruben lost his grandmother to brain cancer three years ago, he promised himself that he would do something significant to honor her memory. By organizing a four-month, 2,659 mile fundraising hike and generous donation to glioblastoma research at City of Hope, he fulfilled that pledge.
July 11, 2016 | Denise Heady
Soon, brain cancer will be treated differently. Just ask scientist Christine Brown, Ph.D., associate director of the T Cell Immunotherapy Laboratory at City of Hope. Brown is on the forefront of a specific kind of immunotherapy: CAR-T cell therapy. Here, Brown tells us how this type of therapy works and what it could mean for future treatment.
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