City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
March 14, 2017 | Denise Heady
More women than ever are surviving breast cancer only to die of secondary brain tumors years after they’ve been declared cancer-free. This is particularly true for patients with the breast cancer subtype HER2-positive. Now City of Hope researchers have discovered how this happens.
January 12, 2017 | Denise Heady
City of Hope's Rahul Jandial, M.D., Ph.D., is making a lasting and global impact by performing and teaching children's brain surgery in developing countries.
January 4, 2017 | Stephanie Smith
Sketches of a brain surgery performed on B., one of several patients in a breakthrough clinical trial for brain cancer at City of Hope. Early results of the trial — describing promising results using CAR-T cells for a 50-year-old patient with an aggressive brain cancer called glioblastoma multiforme — were published recently in the New England Journal of Medicine.
December 30, 2016 | Stephanie Smith
When viewed under a microscope, T cells - sentinels of the immune system whose job inside the body is to seek out foreign invaders - quiver as they surround and consume cancer cells. They were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.
December 29, 2016 | Denise Heady
City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
December 14, 2016 | Denise Heady
One of but a few centers in the United States offering human studies in CAR–T cell therapy, City of Hope is the only center investigating CAR-T cells in injection form administered directly to brain tumors.
September 27, 2016 | Veronique de Turenne
When Nick Troftgruben lost his grandmother to brain cancer three years ago, he promised himself that he would do something significant to honor her memory. By organizing a four-month, 2,659 mile fundraising hike and generous donation to glioblastoma research at City of Hope, he fulfilled that pledge.
May 12, 2016 | Denise Heady
Diane Peacock uses May, Brain Tumor Awareness Month, as a time to recognize, remember and spread awareness about brain cancer - the deadly disease that took her son’s life when he was just four days shy of his 19th birthday.