Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

breakthroughs - Behnam Badie and Christine Brown
$12.8 Million CIRM Grant Awarded to City of Hope for CAR-T Cell Brain Cancer Research

October 16, 2017 | Michael Easterling

Christine Brown, Ph.D., and Behnam Badie, M.D., have received a $12.8 million grant from the California Institute for Regenerative Medicine (CIRM) to fund their work using CAR-T cells to combat brain cancer.

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Leo Wang 1 - HHOW
Leo Wang awarded grant to help support CAR-T cell therapy research for pediatric brain tumors

September 15, 2017 | Denise Heady

To help further City of Hope’s research in CAR-T therapy, Leo Wang, M.D., Ph.D., a dual-trained pediatric oncologist and scientist, was awarded with a Hyundai Young Investigator Grant funded by the Hyundai Hope On Wheels program.

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City of Hope Neurosurgeon, Behnam Badie, M.D.
Patient and Pioneer Richard Grady: His Contributions to Advance Our Research in Treating Brain Tumors Is His Lasting Legacy

August 2, 2017 | Behnam Badie, M.D., F.A.C.S.

My life is devoted to finding a cure for brain cancer. Patients come to us seeking miracles, but often what they give us back is invaluable knowledge. Throughout history, patients have helped revolutionize science and medicine. Many patients, like my dad, do not survive. But they leave behind a legacy of knowledge and hope for other patients today, and for future generations. Richard Grady was that kind of patient.

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Rahul Jandial in the lab
Inside the Lab: Preventing breast cancer from invading the brain

July 24, 2017 | Denise Heady

A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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rahul jandial headshot 256 x 256
Wolf in sheep's clothing: breast cancer cloaks itself in brain proteins to invade the brain

March 14, 2017 | Denise Heady

More women than ever are surviving breast cancer only to die of secondary brain tumors years after they’ve been declared cancer-free. This is particularly true for patients with the breast cancer subtype HER2-positive. Now City of Hope researchers have discovered how this happens.

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