Clinical research nurses: ‘Shepherds’ of the CAR T program
January 9, 2019 | Abe Rosenberg
What's it like to work at the center of a true medical and scientific revolution? It's emotional, often overwhelming. But it’s also a place to witness miracles. Such is the life of the clinical research nurses who staff City of Hope's CAR T cell program.
Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain
October 30, 2018 | Letisia Marquez
A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants.
Inside the Lab: Preventing breast cancer from invading the brain
July 24, 2017 | Denise Heady
A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.
City of Hope researchers find CAR T cell therapy effective in treatment of glioblastoma
July 17, 2017 | Denise Heady
City of Hope researchers have found that using CAR T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
Mother honors son with comedy fundraiser for brain cancer research
May 12, 2016 | Denise Heady
Diane Peacock uses May, Brain Tumor Awareness Month, as a time to recognize, remember and spread awareness about brain cancer - the deadly disease that took her son’s life when he was just four days shy of his 19th birthday.
Study: Researchers develop new method of targeting cancer stem cells
March 3, 2016 | Letisia Marquez
Research into a promising therapeutic target for glioblastoma was recently published in the journal Nature Communications. City of Hope scientists are working to uncover how cancer stem cells grow, and what can be done to stop them from multiplying.
New funding for CAR T cell study gives brain cancer research a boost
October 26, 2015 | City of Hope
Brain cancer is one of the toughest foes a doctor can face. It’s a tenacious form of cancer, inoperable in some cases and lethal in many. But at City of Hope, researchers are exploring new ways to conquer the most serious types of brain tumors in a clinical trial that deploys a patient’s own modified T cells to target cancer at the tumor site.
Brain metastasis from breast cancer: Our research means better treatments (w/VIDEO)
October 17, 2014 | Tami Dennis
A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to regain some sense of normalcy and control over their lives.
Neural stem cells: On the frontier of brain cancer therapy
September 29, 2014 | Sayeh Hirmand
Gliomas, a type of tumor that grows in the brain, are very difficult to treat successfully due to their complex nature. That might not always be the case. Brain tumors can be difficult to treat. A new therapy, using neural stem cells, may offer a powerful new treatment option.
Summer academy student's work on neural stem cells is tribute to father
August 7, 2014 | Darrin Joy
Stevee Rowe has a very personal connection to the research she’s conducting on neural stem cells: Her late father participated in a City of Hope clinical trial involving neural stem cells. Stevee Rowe is researching neural stem cells through the Eugene and Ruth Roberts Summer Student Academy.