Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

City of Hope Neurosurgeon, Behnam Badie, M.D.
Patient and Pioneer Richard Grady: His Contributions to Advance Our Research in Treating Brain Tumors Is His Lasting Legacy

August 2, 2017 | Behnam Badie, M.D., F.A.C.S.

My life is devoted to finding a cure for brain cancer. Patients come to us seeking miracles, but often what they give us back is invaluable knowledge. Throughout history, patients have helped revolutionize science and medicine. Many patients, like my dad, do not survive. But they leave behind a legacy of knowledge and hope for other patients today, and for future generations. Richard Grady was that kind of patient.

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Rahul Jandial in the lab
Inside the Lab: Preventing breast cancer from invading the brain

July 24, 2017 | Denise Heady

A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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Breakthroughs - mother honors son with comedy fundraiser
Mother honors son with comedy fundraiser for brain cancer research

May 12, 2016 | Denise Heady

Diane Peacock uses May, Brain Tumor Awareness Month, as a time to recognize, remember and spread awareness about brain cancer - the deadly disease that took her son’s life when he was just four days shy of his 19th birthday.

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Stem cells 256x256
Study: Researchers develop new method of targeting cancer stem cells

March 3, 2016 | Letisia Marquez

Research into a promising therapeutic target for glioblastoma was recently published in the journal Nature Communications. City of Hope scientists are working to uncover how cancer stem cells grow, and what can be done to stop them from multiplying.

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Breakthroughs - brain cancer research
New funding for CAR-T cell study gives brain cancer research a boost

October 26, 2015 | City of Hope

Brain cancer is one of the toughest foes a doctor can face. It’s a tenacious form of cancer, inoperable in some cases and lethal in many. But at City of Hope, researchers are exploring new ways to conquer the most serious types of brain tumors in a clinical trial that deploys a patient’s own modified T cells to target cancer at the tumor site.

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Brain metastasis patient Joan Rose-Hall
Brain metastasis from breast cancer: Our research means better treatments (w/VIDEO)

October 17, 2014 | Tami Dennis

A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to regain some sense of normalcy and control over their lives.

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Brain cancer
Neural stem cells: On the frontier of brain cancer therapy

September 29, 2014 | Sayeh Hirmand

Gliomas, a type of tumor that grows in the brain, are very difficult to treat successfully due to their complex nature. That might not always be the case. Brain tumors can be difficult to treat. A new therapy, using neural stem cells, may offer a powerful new treatment option.

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Stevee Rowe
Summer academy student's work on neural stem cells is tribute to father

August 7, 2014 | Darrin Joy

Stevee Rowe has a very personal connection to the research she’s conducting on neural stem cells: Her late father participated in a City of Hope clinical trial involving neural stem cells. Stevee Rowe is researching neural stem cells through the Eugene and Ruth Roberts Summer Student Academy.

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