Australian patient travels 9,000 miles for a cure

March 7, 2019 | Michael Easterling

Australian lobster fisherman David Thompson traveled 9,000 miles for treatment at City of Hope after being diagnosed with Stage 4 oropharyngeal cancer. Given just six weeks to live, he is thriving more than a year after participating in an immunotherapy clinical trial.

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Clinical research nurses: ‘Shepherds’ of the CAR T program

January 9, 2019 | Abe Rosenberg

What's it like to work at the center of a true medical and scientific revolution? It's emotional, often overwhelming. But it’s also a place to witness miracles. Such is the life of the clinical research nurses who staff City of Hope's CAR T cell program.

Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain

October 30, 2018 | Letisia Marquez

A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants. 

Inside the Lab: Preventing breast cancer from invading the brain

July 24, 2017 | Denise Heady

A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.

City of Hope researchers find CAR T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

Mother honors son with comedy fundraiser for brain cancer research

May 12, 2016 | Denise Heady

Diane Peacock uses May, Brain Tumor Awareness Month, as a time to recognize, remember and spread awareness about brain cancer - the deadly disease that took her son’s life when he was just four days shy of his 19th birthday.

Study: Researchers develop new method of targeting cancer stem cells

March 3, 2016 | Letisia Marquez

Research into a promising therapeutic target for glioblastoma was recently published in the journal Nature Communications. City of Hope scientists are working to uncover how cancer stem cells grow, and what can be done to stop them from multiplying.

New funding for CAR T cell study gives brain cancer research a boost

October 26, 2015 | City of Hope

Brain cancer is one of the toughest foes a doctor can face. It’s a tenacious form of cancer, inoperable in some cases and lethal in many. But at City of Hope, researchers are exploring new ways to conquer the most serious types of brain tumors in a clinical trial that deploys a patient’s own modified T cells to target cancer at the tumor site.