Landmark human insulin study marks 40-year anniversary

January 29, 2019 | Michael Easterling

In January 1979, the National Academy of Sciences published a paper about an innovative discovery at City of Hope that would forever change how diabetes is treated. Arthur Riggs, Ph.D., and Keiichi Itakura, Ph.D., revolutionized diabetes treatment when they made a novel gene, one that coded for human insulin.

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Vanessa Jonsson, Ph.D.: An engineer tackles CAR T cell therapy

February 13, 2019 | City of Hope

Vanessa Jonsson, Ph.D., focuses on chimeric antigen receptor (CAR) T cell therapy. Using such tools as computational analysis and mathematical modeling, she examines the complex interactions between the tumor, the patient’s immune system and the therapy to learn how the tumor evades the immune response.

Emerging tools prove effective against lymphedema

January 30, 2019 | Alison Shore

City of Hope is on a quest to minimize — and perhaps one day eradicate — lymphedema, a residual effect of cancer that produces swelling ranging from mild to uncomfortable to positively painful.

Breast cancer survivor starts living a ‘purposeful life’

December 18, 2018 | Zen Vuong

Seven City of Hope patients will welcome the New Year atop City of Hope’s 47th Rose Parade float, “Harmony of Hope.” Meet Candida Celaya, a breast cancer survivor who is using her second chance at life to give back to the community.

Can breast implants cause cancer?

November 30, 2018 | Samantha Bonar

Leslie Popplewell, M.D., discusses a recent NBC News report that highlighted the small but apparently growing risk of a rare kind of lymphoma in women who have received breast implants.

Minor diet changes can affect cancer risk, researcher finds

November 9, 2018 | City of Hope

On one hand, City of Hope's Rowan Chlebowski, M.D., Ph.D., is a medical oncologist and breast cancer expert. On the other, he’s a scientist specializing in observational studies who ranks among the most cited researchers in the world.

First-of-its-kind CAR T clinical trial enrolls HER2+ breast cancer patients with brain metastases

October 30, 2018 | City of Hope

City of Hope is now enrolling patients in a phase 1 trial evaluating the safety and efficacy of CAR T cell therapy in patients with HER2+ breast cancer that has metastasized to the brain.

Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain

October 30, 2018 | Letisia Marquez

A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants. 

'I don't have an expiration date': breast cancer patient finds strength after diagnosis

October 24, 2018 | Maxine Nunes

City of Hope breast cancer patient Dani Ghezzi's story is one to take inspiration from, but also begins as a cautionary tale for early detection.

A triple-negative breast cancer trial has its first success story

October 12, 2018 | Maxine Nunes

Linda Collins's outlook was bleak, thanks to her triple-negative breast cancer diagnosis, until City of Hope oncologist Yuan Yuan, M.D., Ph.D. helped develop a revolutionary new trial to help her.