Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Behnam Badie in Surgery
MEET OUR DOCTORS: Behnam Badie on why ‘being a neurosurgeon is not enough’

November 2, 2017 | Denise Heady

Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's. 

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Breakthroughs - brain tumors and cancer - what you need to know - 256x256
Brain tumors and cancer: what you need to know

November 1, 2017 | Denise Heady

Say the words “brain tumor” and most people will likely think of cancer. But there’s reason for optimism - recent advances in screening and treatment, such as CAR-T cell therapy, mean patient outcomes and quality of life are continuing to improve.

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CAR T Illuminated
City of Hope to Provide First FDA-approved CAR-T Cell Therapy for Some Types of Lymphoma

October 18, 2017 | City of Hope

City of Hope will be the one of the first authorized centers in the nation to provide axicabtagene ciloleucel, which the U.S. Food and Drug Administration (FDA) announced today is the first approved CAR-T therapy for adult patients who have not responded to or who have relapsed after at least two other kinds of treatment.

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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Leo Wang
Meet our doctors: How Leo Wang is revolutionizing the way that pediatric and blood cancers are treated

March 17, 2017 | Denise Heady

Dual-trained pediatric oncologist and scientist Leo Wang, M.D., Ph.D., is working in the lab to understand how blood cells develop and grow, and plans to use that information to help patients with cancer live longer and experience fewer side effects of treatment.

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breakthroughs - t cells
INSIDE THE LAB: Tracking T cells in the brain

January 27, 2017 | Denise Heady

City of Hope researchers have seen initial success treating brain cancer patients with CAR-T cell therapy, yet questions still linger about what exactly happens to these cells once they disperse through the brain. A new imaging technique may be the answer.

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