Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

breakthroughs - aids
World AIDS Day: A Functional Cure Is in Sight

December 1, 2017 | Samantha Bonar

There has been great progress made in the fight against HIV/AIDS, and continued efforts to end this global epidemic. Advances, such as anti-retroviral therapy, have revolutionized HIV treatment. Now, researchers are edging closer to the ultimate goal: a cure.

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Lung Cancer Survivor Story | City of Hope
Advanced Lung Cancer Patient: ‘I’m Not About to Go Quietly into the Night’

November 30, 2017 | Julia F.

Julie F., 59, of Wisconsin, survived advanced small cell lung cancer after 29 rounds of chemotherapy, five weeks of radiation and experimental immunotherapy. This is her story.

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Hybrid Nurse Alpha Clinic | City of Hope
City of Hope’s Alpha Clinic Plots ‘the Future of Nursing’

November 3, 2017 | Wayne Lewis

According to a new paper in Stem Cells Translational Medicine, the authors identify the role of a nurse qualified in both patient care and research protocols, the so-called “hybrid nurse” — a homegrown City of Hope innovation — as an important component of their success in the development of the Alpha Clinic.

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Lusi Tumyan
City of Hope Testing Novel Freezing Technique on Early-Stage Breast Cancer

August 24, 2017 | Samantha Bonar

City of Hope is among just a handful of facilities in the country — and one of only two in California — participating in a clinical trial of an exciting new way to treat breast cancer by freezing the tumor.

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Rahul Jandial in the lab
Inside the Lab: Preventing breast cancer from invading the brain

July 24, 2017 | Denise Heady

A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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patel sunita 256x256
City of Hope Researcher Receives Grant to Improve Cognitive Outcomes in Young Cancer Patients

July 7, 2017 | Samantha Bonar

Sunita Patel, Ph.D., a neuropsychologist in the Population Sciences and Supportive Care Medicine departments at City of Hope, has received a $1.22 million grant from the American Cancer Society to test a new approach toward preventing long-term chemotherapy-related cognitive side effects in childhood cancer survivors from bilingual and Spanish-speaking families.

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robert w chen md 256x256
Immunotherapy Drug Shown Safe and Effective in Treating Hodgkin Lymphoma

June 29, 2017 | Katie Neith

Clinical trial results in positive outcomes for patients with relapsed or treatment-resistant disease. Hodgkin lymphoma is typically considered to be one of the most curable forms of cancer, but some with the disease relapse or find that their cancer is resistant to treatment. For patients like this, a fully human monoclonal antibody called avelumab has shown promising results in a phase 1 clinical trial for safety and efficacy.

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