Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

breakthroughs - Behnam Badie and Christine Brown
$12.8 Million CIRM Grant Awarded to City of Hope for CAR-T Cell Brain Cancer Research

October 16, 2017 | Michael Easterling

Christine Brown, Ph.D., and Behnam Badie, M.D., have received a $12.8 million grant from the California Institute for Regenerative Medicine (CIRM) to fund their work using CAR-T cells to combat brain cancer.

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Genetics
Really Big Data: How Genomics Is Poised to Reshape Cancer Care

September 28, 2017 | Abe Rosenberg

The exploding field of cancer genomics is enabling that kind of prediction for a growing number of inherited cancers, like identifying one of the many genes beyond BRCA1 and BRCA2 gene mutations linked to breast cancer.

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Lusi Tumyan
City of Hope Testing Novel Freezing Technique on Early-Stage Breast Cancer

August 24, 2017 | Samantha Bonar

City of Hope is among just a handful of facilities in the country — and one of only two in California — participating in a clinical trial of an exciting new way to treat breast cancer by freezing the tumor.

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Rahul Jandial in the lab
Inside the Lab: Preventing breast cancer from invading the brain

July 24, 2017 | Denise Heady

A study led by City of Hope neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., offers novel insights on how cancer cells in HER2-positive breast cancer develop the ability to break through the blood-brain barrier and, ultimately, how they can be stopped.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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patel sunita 256x256
City of Hope Researcher Receives Grant to Improve Cognitive Outcomes in Young Cancer Patients

July 7, 2017 | Samantha Bonar

Sunita Patel, Ph.D., a neuropsychologist in the Population Sciences and Supportive Care Medicine departments at City of Hope, has received a $1.22 million grant from the American Cancer Society to test a new approach toward preventing long-term chemotherapy-related cognitive side effects in childhood cancer survivors from bilingual and Spanish-speaking families.

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robert w chen md 256x256
Immunotherapy Drug Shown Safe and Effective in Treating Hodgkin Lymphoma

June 29, 2017 | Katie Neith

Clinical trial results in positive outcomes for patients with relapsed or treatment-resistant disease. Hodgkin lymphoma is typically considered to be one of the most curable forms of cancer, but some with the disease relapse or find that their cancer is resistant to treatment. For patients like this, a fully human monoclonal antibody called avelumab has shown promising results in a phase 1 clinical trial for safety and efficacy.

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Dan Rojas
HIV Stem Cell Trial Patient Strives, Cycles for a Cure

June 13, 2017 | Samantha Bonar

Dan Rojas, 31, who has been living with HIV since 2011, is one of a handful of brave patients participating in a groundbreaking study at City of Hope that seeks a cure for AIDS.

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