Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

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Cancer Urban Legend: Cancer Runs in My Family, I Can’t Reduce My Risk

February 24, 2017 | Abe Rosenberg

Tell people that cancer is “genetic” and they start to wonder: "Do I inherit cancer the same way I inherited my mother's green eyes?" No, you don't. Almost never. By far, most cancers occur because of something risky we did, or something risky we were exposed to. Think smoking and lung cancer. Workplace asbestos and mesothelioma. Obesity and ... well, lots of things.

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Stacy Gray, M.D. - Profile Photo
Genetic Tests Showing Small Cancer Risk Do Not Change Behavior

December 13, 2016 | Katie Neith

Swabbing the inside of your mouth and sending a saliva sample through the mail for analysis is one of the easiest and least invasive ways to test for a multitude of health risks. But a new study by City of Hope researcher Stacy Gray, M.D., reveals that at-home genetic tests don’t change behavior, even when they reveal an elevated risk of cancer.

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Stacy Gray, M.D. - Profile Photo
Genetic Tests Showing Small Cancer Risk Do Not Change Behavior

December 13, 2016 | Katie Neith

Swabbing the inside of your mouth and sending a saliva sample through the mail for analysis is one of the easiest and least invasive ways to test for a multitude of health risks. But a new study by City of Hope researcher Stacy Gray, M.D., reveals that at-home genetic tests don’t change behavior, even when they reveal an elevated risk of cancer.

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Don and Lois Hoffman
Breast Cancer: 'It's supposed to be a woman's disease'

June 15, 2016 | Stephanie Smith

Male breast cancer is unusual. Breast cancer being cast as “a woman’s disease” means men aren’t checking for it and therefore tend to be diagnosed later. Despite the paltry number of cases, being vigilant is important for men - a lesson Don Hoffman learned the hard way.

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Veliparib molecular formula
Biomarker linked to survival and treatment for BRCA-positive breast cancer patients

June 8, 2016 | H. Chung So

For breast cancer patients with BRCA gene mutations, compounds called poly ADP ribose (or PAR) can help determine treatment response and clinical outcomes.

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breast cancer genetic testing
Breast cancer genetic testing: How one family took control

January 5, 2015 | Nicole White

Betsy Sauer and her four daughters share plenty in common. They’re smart and successful.  They’re funny, ranging from wryly witty to wickedly hilarious. Their hobbies tend toward the active and adventurous: hiking, rock climbing, skiing, swimming, fishing, kayaking, yoga and horseback riding.

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Genes and cancer risk
Cancer in your family history? Your genes are not your destiny

November 21, 2014 | Valerie Zapanta

When it comes to cancer, your family history may provide more questions than answers: How do my genes increase my risk for cancer? No one in my family has had cancer; does that mean I won’t get cancer? What cancers are common in certain populations and ethnicities? City of Hope experts have some guidance.

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Cancer and genes
What are my genes telling me about my cancer risk?

October 27, 2014 | Valerie Zapanta

Genetics, genes, genome, genetic risk ... Such terms are becoming increasingly familiar to even nonresearchers as studies and information about the human make-up become more extensive and more critical.

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Breast cancer risk: 6 things you can do to reduce (not eliminate) risk

October 14, 2014 | Nicole White

The leading risk factor for breast cancer is simply being a woman. The second top risk factor is getting older. Many breast cancer risk factors, such as gender and aging, cannot be controlled. But lacing up for a walk a few times a week can put a dent in breast cancer risk.

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ASCO 2014: Experimental drug has potential for BRCA-linked breast cancer

May 26, 2014 | Hiu Chung So

For patients with BRCA mutation-associated breast cancer, the experimental drug ABT-888 — also known as veliparib — is showing promise as a treatment, according to phase II clinical trial results that will be reported at the upcoming annual meeting of the American Society of Clinical Oncology.

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