March 13, 2018 | Denise Heady
Fourteen years ago, neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., began to travel to underserved countries to perform brain surgeries on disadvantaged children.
Meet Our CAR T Team: Christine Brown, Ph.D.
January 26, 2018 | Abe Rosenberg
Christine Brown, Ph.D., co-leads the T Cell Therapeutics Research Laboratory, along with Stephen J. Forman, M.D., which to date has treated more than 100 patients in seven clinical trials, with aggressive goals of opening four new clinical studies within the year.
MEET OUR DOCTORS: Behnam Badie on why ‘being a neurosurgeon is not enough’
November 2, 2017 | Denise Heady
Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's.
City of Hope researchers find CAR T cell therapy effective in treatment of glioblastoma
July 17, 2017 | Denise Heady
City of Hope researchers have found that using CAR T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
CAR T cells: ‘Soldiers of the Immune System’
July 10, 2017 | Stephanie Smith
T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.
New Compound Discovered in the Battle Against Brain Cancer
January 30, 2017 | City of Hope
A study led by scientists at the Translational Genomics Research Institute (TGen), a City of Hope affiliate, has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer.
Inside CAR T Cell Glioblastoma Surgery
January 4, 2017 | Stephanie Smith
Sketches of a brain surgery performed on B., one of several patients in a breakthrough clinical trial for brain cancer at City of Hope. Early results of the trial — describing promising results using CAR T cells for a 50-year-old patient with an aggressive brain cancer called glioblastoma multiforme — were published recently in the New England Journal of Medicine.
Graduate student spotlight: Dongrui Wang and cancer immunotherapy
October 17, 2016 | Denise Heady
Graduate student Dongrui Wang’s poster presentation at the 19th annual American Society of Gene & Cell Therapy was selected as the conference’s Outstanding Poster Presentation for his research initiatives in gene and cell therapy. Here Wang talks about what motivated him to pursue a career in science, what keeps him inspired and the innovative research he is working on at City of Hope.