Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Behnam Badie in Surgery
MEET OUR DOCTORS: Behnam Badie on why ‘being a neurosurgeon is not enough’

November 2, 2017 | Denise Heady

Driven in part by the plight of his patients and his father, chief of neurosurgery Behnam Badie, M.D., spends nearly as much time in the laboratory as he does in the operating room. He wants to help not just today's patients, but tomorrow's. 

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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brain tumor
New Compound Discovered in the Battle Against Brain Cancer

January 30, 2017 | City of Hope

A study led by scientists at the Translational Genomics Research Institute (TGen), a City of Hope affiliate, has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer.

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Inside CAR T 256 x 256
Inside CAR-T Cell Glioblastoma Surgery

January 4, 2017 | Stephanie Smith

Sketches of a brain surgery performed on B., one of several patients in a breakthrough clinical trial for brain cancer at City of Hope. Early results of the trial — describing promising results using CAR-T cells for a 50-year-old patient with an aggressive brain cancer called glioblastoma multiforme — were published recently in the New England Journal of Medicine.

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Breakthroughs - Dongrui Wang
Graduate student spotlight: Dongrui Wang and cancer immunotherapy

October 17, 2016 | Denise Heady

Graduate student Dongrui Wang’s poster presentation at the 19th annual American Society of Gene & Cell Therapy was selected as the conference’s Outstanding Poster Presentation for his research initiatives in gene and cell therapy. Here Wang talks about what motivated him to pursue a career in science, what keeps him inspired and the innovative research he is working on at City of Hope.

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Nick Troftgruben and his grandmother, Vonnie
19-year-old honors grandmother by raising money for brain cancer research

September 27, 2016 | Veronique de Turenne

When Nick Troftgruben lost his grandmother to brain cancer three years ago, he promised himself that he would do something significant to honor her memory. By organizing a four-month, 2,659 mile fundraising hike and generous donation to glioblastoma research at City of Hope, he fulfilled that pledge.

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