City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
July 17, 2018 | Denise Heady
City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.
July 17, 2017 | City of Hope
Cancer care has come a long way. Surgery, chemotherapy and radiation have traditionally been the three pillars of cancer care, and they are still important treatments. But in recent years, newer “targeted therapies” have come on the scene.
July 10, 2017 | Stephanie Smith
When viewed under a microscope, T cells - sentinels of the immune system whose job inside the body is to seek out foreign invaders - quiver as they surround and consume cancer cells. They were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.
June 8, 2017 | Denise Heady
The evolution of cancer treatment continues to progress, particularly for gynecologic cancers. More women are becoming cancer survivors and physicians, surgeons and researchers now have a better understanding of genetic alteration in cancer development, carving the way for better and more individualized treatments.
June 5, 2017 | Cary A. Presant, M.D.
Here at ASCO 2017 in Chicago, we’ve been hearing about promising new clinical trials that have shown that immunotherapy can control some of the most resistant cancers.
May 26, 2017 | Samantha Bonar
Four years ago, Mark Paolera, now 39, was busy enjoying the typical active California lifestyle, including mountain biking, hiking and deep-sea fishing. After a battery of tests, Paolera was diagnosed with Stage 2 Hodgkin lymphoma in May of 2014.
January 6, 2017 | Samantha Bonar
Although it is uncommon in the U.S., stomach cancer is a serious, often devastating disease. But less than 25 percent of patients who are diagnosed with stomach cancer in the U.S. survive for five years. City of Hope’s physicians and scientists are committed to changing this.
December 23, 2016 | Dory Benford
Great strides have been made in pediatric cancer and childhood disease treatment over the past few decades, and recent advances in the areas of gene therapy, immunotherapy and targeted therapy will continue to move the field forward in 2017. We spoke to Joseph Rosenthal, M.D., M.H.C.M., professor and chair of the Department of Pediatrics at City of Hope, about the most significant developments he anticipates in pediatric research and treatment.
December 23, 2016 | Katie Neith
Peter P. Lee, M.D., a City of Hope oncologist, has for 20 years been interested in treating cancer by stimulating or enhancing a person’s own immune system. This approach, called immunotherapy, has gained much attention in recent years. Lee's outlook for 2017 is full of promise for a more personalized approach to the disease.
December 14, 2016 | City of Hope
City of Hope has the clinical and scientific expertise to house the entire clinical trial process on its campus — including collecting the cells, manufacturing the lentivirus, modifying and replicating the cells and reinfusing them.