Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

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The Gold Standard: City of Hope’s Pediatric Musculoskeletal Tumor Program

August 3, 2017 | Travis Marshall

Pediatric musculoskeletal tumors and sarcomas are so rare and diverse that it’s almost impossible for a single physician to effectively treat them. But City of Hope is uniquely equipped to provide rapid and comprehensive treatment for these highly aggressive cancers.

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breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2017 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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George Hajjar Bio Photo
Targeted Therapy 101: A Primer

July 17, 2017 | City of Hope

Cancer care has come a long way. Surgery, chemotherapy and radiation have traditionally been the three pillars of cancer care, and they are still important treatments. But in recent years, newer “targeted therapies” have come on the scene.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

T cells were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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Mehdi Kebria
Making headway in the treatment of gynecologic cancers

June 8, 2017 | Denise Heady

The evolution of cancer treatment continues to progress, particularly for gynecologic cancers. More women are becoming cancer survivors and physicians, surgeons and researchers now have a better understanding of genetic alteration in cancer development, carving the way for better and more individualized treatments.

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Presant-Cary
Live from ASCO: Immunotherapy Is a Revolution in Medicine

June 5, 2017 | Cary A. Presant, M.D.

Here at ASCO 2017 in Chicago, we’ve been hearing about promising new clinical trials that have shown that immunotherapy can control some of the most resistant cancers.

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Mark Paolera
Immunotherapy Gives Hodgkin Lymphoma Patient a Second Chance

May 26, 2017 | Samantha Bonar

Four years ago, Mark Paolera, now 39, was busy enjoying the typical active California lifestyle, including mountain biking, hiking and deep-sea fishing. After a battery of tests, Paolera was diagnosed with Stage 2 Hodgkin lymphoma in May of 2014.

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Yanghee Woo bio portrait
New Treatments and Personalized Care Offer Hope for Stomach Cancer Patients

January 6, 2017 | Samantha Bonar

Although it is uncommon in the U.S., stomach cancer is a serious, often devastating disease. But less than 25 percent of patients who are diagnosed with stomach cancer in the U.S. survive for five years. City of Hope’s physicians and scientists are committed to changing this.

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Advances: 2017 brings new therapies, new hope to those battling pediatric cancer

December 23, 2016 | Dory Benford

Great strides have been made in pediatric cancer and childhood disease treatment over the past few decades, and recent advances in the areas of gene therapy, immunotherapy and targeted therapy will continue to move the field forward in 2017. We spoke to Joseph Rosenthal, M.D., M.H.C.M., professor and chair of the Department of Pediatrics at City of Hope, about the most significant developments he anticipates in pediatric research and treatment.

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Lee-Peter
Advances: New Immunotherapy Treatments for Breast Cancer in 2017

December 23, 2016 | Katie Neith

Peter P. Lee, M.D., a City of Hope oncologist, has for 20 years been interested in treating cancer by stimulating or enhancing a person’s own immune system. This approach, called immunotherapy, has gained much attention in recent years. Lee's outlook for 2017 is full of promise for a more personalized approach to the disease.

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