Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

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Targeted Therapy 101: A Primer

July 17, 2017 | City of Hope

Cancer care has come a long way. Surgery, chemotherapy and radiation have traditionally been the three pillars of cancer care, and they are still important treatments. But in recent years, newer “targeted therapies” have come on the scene.

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Meditopes: Hitching cancer drugs to antibodies (w/VIDEO)

July 1, 2014 | Nicole White

Scientists have long searched for ways to bolster the immune system to fight diseases that seem to evade it, including cancer. City of Hope scientists discovered what they call a meditope, an opening in the center of an antibody and a peptide that fits neatly into it, creating the perfect "hitch" that allows medicines to be attached to the antibodies for delivery to tumor sites.

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