City of Hope Reveals Vision for World-Class Cancer Care in Orange County

June 25, 2019 | City of Hope

City of Hope has accelerated its plans for a $1 billion comprehensive cancer campus in Orange County, bringing highly specialized cancer care, clinical trials, precision medicine and early detection to the nation’s sixth most populous county.

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Scientists gaining on graft-versus-host disease

May 2, 2019 | Abe Rosenberg

Scientist Defu Zeng is tackling graft-versus-host disease, a common side effect of bone marrow transplants, taking several tacks that include modulating T cells and fine-tuning specific proteins and antibodies.

Targeting a cancer cell’s “master switch”

May 9, 2016 | City of Hope

According to a new study published in the prestigious scientific journal, Immunity, scientists at City of Hope have unlocked a key component of STAT3 activation, a gene that has long been associated with tumor cell growth and antitumor immune suppression. By exploring how STAT3 is activated in B cells, a major type of immune cell, our researchers have identified a novel target for cancer therapy.

Beating prostate cancer: ‘We’re taking off the brakes’

March 24, 2016 | City of Hope

Researchers at City of Hope believe they are on the verge of significant headway in the treatment of advanced prostate cancer, thanks to new thinking and “staggering” early success.

Taking off the brakes to beat prostate cancer

March 24, 2016 | City of Hope

Researchers believe they are on the verge of significant headway in the treatment of advanced prostate cancer with a focus on immunotherapy and CAR T cell therapy.

Antibodies discovery could revolutionize the treatment of cancer

February 2, 2016 | Elise Lamar

Stat, Myc, Myb, Fos, Ras, and Fox: Those bland monosyllables, unfamiliar to most of us, command the respect and fear of oncologists and cancer researchers worldwide. Why? Because they name proteins that drive uncontrollable cell division, metastasis, and/or drug resistance in numerous cancers.

March Grad Student Forum: Jenny Wang

March 21, 2014 | Jenny Wang

Successful breast cancer treatment is often hindered by chemoresistance, metastasis, and tumor recurrence.  The existence of a small population of cells, called cancer stem cells, is thought to contribute to these complications.