City of Hope Reveals Vision for World-Class Cancer Care in Orange County

June 25, 2019 | City of Hope

City of Hope has accelerated its plans for a $1 billion comprehensive cancer campus in Orange County, bringing highly specialized cancer care, clinical trials, precision medicine and early detection to the nation’s sixth most populous county.

Continue Reading

Diagnosis and treatment at the same time? With theranostics, it's possible

March 27, 2019 | Zen Vuong

A City of Hope scientist and his colleagues have developed a user-friendly approach to creating “theranostics” — therapy combined with diagnostics — that target specific tumors and diseases.

Study explores why glioblastoma affects sexes differently

February 25, 2019 | City of Hope

A nationwide team of researchers that includes City of Hope’s Translational Genomics Research Institute (TGen) has identified molecular differences that explain why men die of glioblastoma, a type of brain cancer, at nearly twice the rate of women.

Vanessa Jonsson, Ph.D.: An engineer tackles CAR T cell therapy

February 13, 2019 | City of Hope

Vanessa Jonsson, Ph.D., focuses on chimeric antigen receptor (CAR) T cell therapy. Using such tools as computational analysis and mathematical modeling, she examines the complex interactions between the tumor, the patient’s immune system and the therapy to learn how the tumor evades the immune response.

Clinical research nurses: ‘Shepherds’ of the CAR T program

January 9, 2019 | Abe Rosenberg

What's it like to work at the center of a true medical and scientific revolution? It's emotional, often overwhelming. But it’s also a place to witness miracles. Such is the life of the clinical research nurses who staff City of Hope's CAR T cell program.

Groundbreaking new CAR T cell trial opens for patients with breast cancer that has spread to the brain

October 30, 2018 | Letisia Marquez

A new City of Hope chimeric antigen receptor (CAR) T cell trial – the first to focus on HER2-postive breast cancer patients with brain metastases – is now enrolling potential participants. 

CIRM Awards City of Hope Researchers $3.7 million to Develop Glioblastoma Clinical Trial

September 28, 2018 | Letisia Marquez

California Institute for Regenerative Medicine has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients, which would genetically alter blood stem cells to better tolerate chemotherapy.

A breakthrough treatment for melanoma metastasized to the brain

September 6, 2018 | Maxine Nunes

A remarkable new study, groundwork for which was begun by City of Hope oncologist Kim Margolin, M.D., brings new hope to people with melanoma that has metastasized to the brain.

City of Hope Awarded $3.7 million to Develop Glioblastoma Clinical Trial

June 29, 2018 | Letisia Marquez

California Institute for Regenerative Medicine has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients, which would genetically alter blood stem cells to better tolerate chemotherapy.