Andrew Nguyen, M.D.

310-750-1715
Andrew Nguyen, M.D.
Surgical Oncologist
Clinical Expertise
Breast Cancer
Colorectal Surgery
Endocrine Surgery
Hepatobiliary and Pancreatic Surgery
Melanoma and Sarcoma Surgery
Upper Gastrointestinal and Mixed Tumor Surgery
Appointments
Assistant Clinical Professor, Division of Surgical Oncology, Department of Surgery
Clinical Teams
Colorectal Surgery
Endocrine Surgery
Surgery
Surgery — Surgical Oncology
"I am passionate about truly understanding my patients, characterizing their disease, identifying the best strategy, and then providing the most appropriate, personalized care for each individual patient." — Dr. Nguyen
Andrew Nguyen, M.D., is an assistant clinical professor in the Division of Surgical Oncology in the Department of Surgery at City of Hope. He received his Bachelor of Science from the University of California San Diego, where he graduated Phi Beta Kappa, magna cum laude. After attending medical school at New York University School of Medicine, he received his surgical training at the David Geffen School of Medicine at UCLA, followed by a complex surgical oncology fellowship at City of Hope. Dr. Nguyen was awarded a UCLA-CURE NIH T32 Training Grant and the Gerald S. Levey Surgical Research Award. His research work has centered on dendritic cell biology and targeting MicroRNA-regulated networks in pancreatic cancer. Dr. Nguyen sees general surgical oncology patients, including melanoma, sarcoma and gastrointestinal cancers at City of Hope’s South Bay location.
Location
Education & Experience
Degrees

  • 2011, M.D., New York University School of Medicine, New York, NY

  • 2007, B.S. in Bioengineering, University of California, San Diego, La Jolla, CA

Fellowship

  • 2018-2020, Complex General Surgical Oncology Fellow, City of Hope Duarte, CA

  • 2008, Internal Medicine Summer Research Fellowship, New York University, School of Medicine, New York, NY

Residency

  • 2012-2018, General Surgery Resident, David Geffen School of Medicine at UCLA, Los Angeles, CA

Internship

  • 2011-2012, General Surgery Internship, David Geffen School of Medicine at UCLA, Los Angeles, CA

Professional Experience

  • 2020-present, Assistant Clinical Professor, Department of Surgery, Division of Surgical Oncology, City of Hope, South Bay, CA

Research
Lab Members
2013-2016, Study of Histone Deacetylase Inhibitors in Pancreatic Cancer Microenvironment, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA. Mentor: Timothy Donahue, M.D.
  • In vitro and in vivo experimentation involving the effects of HDAC inhibitor in the pancreatic cancer micro-environment
2013-2015, Revising Surgical Indications for Intraductal Papillary Mucinous Neoplasms, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA. Mentor: Timothy Donahue, M.D.
  • Developed a database of patients since 1996 who underwent pancreatic resection for IPMN at UCLA
  • Data analysis, manuscript writing
2013-2017, Targeting MicroRNA-Regulated Networks in Human Pancreatic Cancer, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA. Mentor: Timothy Donahue, M.D.
  • In vivo experiments involving pancreatic cancer cells and miR-modulated fibroblasts
  • In vitro co-culture experiments of pancreatic cancer cells and primary pancreatic fibroblasts
2010-2011, Divergent population of lipid-laden hepatic dendritic cells, Department of Surgery, New York University School of Medicine, New York, NY. Mentor: George Miller, M.D.
  • In vivo experiments involving isolation of hepatic dendritic cells
  • Flow cytometry of hepatic immune cells
  • Data analysis, manuscript writing, critical revisions
  • 2012, published in Gastroenterology
2010-2011, Dendritic cells protect against acute acetaminophen toxicity, Department of Surgery, New York University School of Medicine, New York, NY. Mentor: George Miller, M.D.
  • In vivo cellular depletion of dendritic cells
  • Histologic evaluation of murine liver specimens
  • Data analysis, critical revisions
  • 2011, published in Hepatology
2010-2011, Dendritic cells in intrahepatic inflammation and fibrosis in non-alcoholic steatohepatitis, Department of Surgery, New York University School of Medicine, New York, NY. Mentor: George Miller, M.D.
  • Experience with isolation of hepatic non-parenchymal cells
  • Basic immunological assay comparing subsets of liver dendritic cells
2009-2011, Dendritic cells in pancreatitis and pancreatic carcinogenesis, Department of Surgery, New York University School of Medicine, New York, NY. Mentor: George Miller, M.D.
  • Role of dendritic cell in pathogenesis of pancreatitis
  • Role of dendritic cell in inflammation to cancer transition in pancreas
  • In vivo cellular depletion of dendritic cells
  • Experience with cell culture, flow cytometry, and histological evaluation of murine and human pancreas specimens
  • Data analysis, manuscript writing, critical revisions
  • 2011, accepted in Journal of Experimental Medicine; published in Gastroenterology
2009-2011, Prospective Clinical Pancreatitis Database, New York University School of Medicine, New York, NY. Mentors: Steven Cohen, D.O., Department of Surgery
  • Project planning and data collecting for clinical database for Ranson criteria re-stratification and development of improved prognostic criteria
  • Developed the protocol in collection of specimens and bodily fluid and the subsequent processing for later analysis
2008-2009, Cardiac Magnetic Resonance Imaging Analysis, Tisch Hospital, New York, NY. Mentor: Barbara Srichai, M.D., Department of Radiology
  • Evaluated cardiac anatomy and function, using a Siemens Syngo workstation
2008, Cardiac Magnetic Resonance Imaging Clinical Database, Manhattan Campus of VA NY Harbor Healthcare System, New York, NY. Mentor: Robert Donnino, M.D., Department of Cardiology
  • Developed a clinical research database of cardiac MRI Manhattan VA patients
  • 2011, published in American Journal of Cardiology
Awards & Memberships
Awards

  • 2014, H & H Lee Surgical Research Travel Award, David Geffen School of Medicine at UCLA, Los Angeles, CA

  • 2014, 2015, Outstanding Student Teaching Award, David Geffen School of Medicine at UCLA, Los Angeles, CA

  • 2014, CURE Annual Research Meeting, Abstract of Distinction, David Geffen School of Medicine at UCLA, Los Angeles, CA

  • 2013-2015, UCLA-CURE NIH T32 Gastroenterology Training Grant, David Geffen School of Medicine at UCLA, Los Angeles, CA

  • 2012, Gerald S. Levey Surgical Research Award, David Geffen School of Medicine at UCLA, Los Angeles, CA

  • 2011, AAS Outstanding Medical Student Award, Annual Academic Surgical Congress, Huntington Beach, CA

  • 2010, AAS Student Research Award, Association of Academic Surgery, Los Angeles, CA

Publications
  • Donnino R, Nguyen AH, Sedlis SP, Srichai M. Myocardial scar in diabetics and non-diabetics with ischemic heart disease as assessed by magnetic resonance imaging. Journal of Cardiovascular Magnetic Resonance, 2009.
  • Donnino R, Michelin K, Aizer A, Nguyen AH, Babb J, Srichai M. Predictive value of electrocardiographic criteria for regional wall thickness in patients with cardiomyopathy. Journal of Cardiovascular Magnetic Resonance, 2010.
  • Connolly MK, Ayo D, Malhotra A, Hackman M, Bedrosian AS, Ibrahim J, Malhotra A, Ciez-Rubio N, Nguyen AH, Pachter HL, Miller G. Dendritic cell depletion exacerbates acetaminophen hepatotoxicity. Hepatology. 2011. PMID: 21574173.
  • Donnino R, Patel S, Nguyen AH, Sedlis SP, Babb JS, Schwartzbard A, Katz SD, Srichai MB. Comparison of Quantity of Left Ventricular Scarring and Remodeling by Magnetic Resonance Imaging in Patients With Versus Without Diabetes Mellitus and With Coronary Artery Disease. Am J Cardiol. 2011. PMID: 21439536
  • Bedrosian AS*, Nguyen AH*, Hackman M, Connolly MK, Malhotra A, Ibrahim J, et al. Dendritic cells promote pancreatic viability in mice with acute pancreatitis. Gastroenterology. 2011;141(5):1915-26 e1-14. PMCID: 3202684.
  • Marr M, Hemmert K, Nguyen AH, Combs R, Annamalai A, Miller G, et al. Team play in surgical education: a simulation-based study. J Surg Educ. 2012;69(1):63-9. PMCID: 22208835
  • Nguyen AH, Bedrosian AS, Connolly M, Henning J, Medina-Zea V, Cieza-Rubio NE, Dorvil-Castro M, Graffeo C, Hackman M, Rehman A, Ibrahim J, Miller G. The Role of Dendritic Cell and Pancreatic Stellate Cell Cross-Talk in Chronic Pancreatitis. J Surg Research. 2012;172(2):223.
  • Ibrahim J*, Nguyen AH*, Rehman A, Ochi A, Jamal M, Graffeo CS, et al. Dendritic Cell Populations with Different Concentrations of Lipid Regulate Tolerance and Immunity in Mouse and Human Liver. Gastroenterology. 10/2012. PMCID: 22705178
  • Ochi A*, Nguyen AH*, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, Zambirinis CP, Fallon NC, Rehman A, Pylayeva-Gupta Y, Badar S, Hajdu C, Frey AB, Bar-Sagi D, Miller G. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med. 8/2012 Aug 27;209(9):1671-87. PMID: 22908323
  • Nguyen AH, Donahue TR. Metastatic pancreatic insulinoma with treatment-limiting thrombocytopenia. Am Surg. 2013 Mar;79(3):124-6. PMID: 23461938
  • Abouzeid M, Graffeo CS, Nguyen AH, Marr M, Ayo D, Obeid N, Bryk D, Pachter HL, Cohen S. Disparities Between Public and Private Hospitals Within a Single Academic Center in the Management of Gallstone Pancreatitis. Pancreatology, March 2013.
  • Donahue TR*, Nguyen AH*, Li L, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal MicroRNA-21 Levels Predict Response to 5-Fluorouracil in Patients with Pancreatic Cancer. J Surg Oncol. 2014 Dec;110(8):952-9. PMID: 25132574. PMCID: PMC4232442.
  • Nguyen AH, Toste P, Farrell JJ, Clerkin BM, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. J Gastrointest Surg. 2015 Feb;19(2):258-65. PMID: 25373706. PMCID PMC4305480.
  • Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low Expression of the E3 Ubiquitin Ligase CBL Confers Chemoresistance in Human Pancreatic Cancer and Is Targeted by Epidermal Growth Factor Receptor Inhibition. Clin Cancer Res. 2015 Jan 1;21(1):157-65. PMID: 25348515. PMCID: PMC4286535.
  • Toste PA, Li L, Kadera BE, Nguyen AH, Tran LM, Wu N, Madnick DL, Patel SG, Dawson DW, Donahue TR. p85α is a microRNA target and affects chemosensitivity in pancreatic cancer. J Surg Res. 2015 Jun
  • 15;196(2):285-293. PMID: 25846727.
  • Williams JL, Nguyen AH, Rochefort M, Muthusamy VR, Wainberg ZA, Dawson DW, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Pancreatic cancer patients with lymph node involvement by direct tumor extension have similar survival to those with node-negative disease. J Surg Oncol. 2015 Aug;112(4):396-402. doi: 10.1002/jso.24011. Epub 2015 Aug 25. PMID: 26303811
  • Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-induced Inflammatory Gene Signature and Pro-tumorigenic Phenotype in Pancreatic CAFs via Stress-associated MAPK. Mol Cancer Res. 2016 Mar 15. pii: molcanres.0348.2015. PMID: 26979711
  • Williams JL, Kadera BE, Nguyen AH, Muthusamy VR, Hines OJ, Reber HA, Donahue TR. CA19-9 Normalization During Pre-Operative Treatment Predicts Longer Survival for Patients with Locally Progressed Pancreatic Cancer. J Gastrointest Surg. 2016 Jul;20(7):1331-42. PMID: 27114246.
  • Nguyen AV, Nyberg KD, Scott MB, Welsh AM, Nguyen AH, Wu N, Hohlbauch SV, Geisse NA, Gibb EA, Robertson AG, Donahue TR, Rowat AC. Stiffness of pancreatic cancer cells is associated with increased invasive potential. Integr Biol (Camb). 2016 Oct 20. PMID: 27761545.
  • Nguyen AH, Elliot IA, Wu N, Matsumura C, Vogelauer M, Attar N, Dann A, Ghukasyan R, Toste PA, Patel SG, Williams JL, Li L, Dawson DW, Radu C, Kurdistani SK, Donahue TR. Histone Deacetylase Inhibitors Provoke a Tumor Supportive Phenotype in Pancreatic Cancer Associated Fibroblasts. Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13572. PMID: 27894105.
  • Sugimoto M, Elliott IA, Nguyen AH, Kim S, Muthusamy VR, Watson R, Hines OJ, Dawson DW, Reber HA, Donahue TR. Assessment of a Revised Management Strategy for Patients With Intraductal Papillary Mucinous Neoplasms Involving the Main Pancreatic Duct. JAMA Surg. 2016 Nov 9. JAMA Surg. PMID: 27829085.
  • Nguyen AH, Melstrom LG. Use of imaging as staging and surgical planning for pancreatic surgery. Hepatobiliary Surg Nutr 2019. doi: 10.21037/hbsn.2019.05.04
  • De Andrade JP, Blakely AM, Nguyen AH, Ituarte PHG, Warner SG, Meltrom LG, Lee B, Singh G. Neuroendocrine Tumors of Meckel's Diverticula: Rare but Fare Well. American Surg. 2019 Oct. Accepted.
    *denotes co-first authorship
Ratings & Reviews
Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with five stars being the highest.
Ratings
5.0
Recommend this provider office
5.0
Provider explain in way you understand
5.0
Provider listen carefully to you
5.0
Show respect for what you say
5.0
Spend enough time with you
4.9
Know important info medical history
4.9
Rate provider 0-10
Reviews
12/23/23
He needs to be rated higher than a 5 - Verified patient
11/30/23
Always excellent and always professional - Verified patient
11/30/23
Excellent - Verified patient
11/08/23
Excellent care - Verified patient
10/04/23
Doctor takes his time to answer myQuestions and what I'm to do to get better - Verified patient