City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
April 25, 2017 | City of Hope
Our team of clinical specialists and researchers are pioneering innovative treatments for pediatric cancer and childhood diseases, including advances in gene therapy, immunotherapy and targeted therapy.
April 3, 2017 | Travis Marshall
An upcoming phase 1 clinical trial at City of Hope will look at the effects of CAR-T cells programmed to target a protein called CS-1, which is found on myeloma cells.
March 28, 2017 | Michael Easterling
Patients who have benefited from stem cell therapies funded by CIRM were the focus of the second symposium of the Alpha Stem Cell Clinics Network.
March 7, 2017 | Letisia Marquez
Clinical trial shows promising results from risky procedure, identifies path for personalized therapies. The results were published recently in the journal, Frontiers in Immunology.
February 15, 2017 | Denise Heady
City of Hope case study published in the New England Journal of Medicine reported treatment with reengineered CAR-T cells dramatically improved quality of life for patient with recurrent glioblastoma.
January 9, 2017 | Abe Rosenberg
Everything changed when a Hodgkin lymphoma patient joined a Phase II clinical trial examining the effectiveness of brentuximab vedotin (BV) after a failed transplant. The BV worked immediately, achieving a complete remission which, year after year, proved to be durable beyond anyone's expectations.
December 16, 2016 | City of Hope
While treatment therapies exist for CTCL (MF/SS) and other cutaneous lymphomas, the most prevalent therapies have not yet offered consistent and sustained response or cure. Our multidisciplinary team continues to provide leadership in research and in developing therapies to advance a cure.
December 14, 2016 | Denise Heady
One of but a few centers in the United States offering human studies in CAR–T cell therapy, City of Hope is the only center investigating CAR-T cells in injection form administered directly to brain tumors.
December 14, 2016 | City of Hope
Data published in Blood supports ongoing phase 2 trial of Triplex in allogeneic hematopoietic stem cell transplant recipients.
December 7, 2016 | City of Hope
Numerous clinical trials, which lay the groundwork for novel approaches to lymphoma and multiple myeloma therapies, could ultimately lead to new treatments that improve survival and quality of life for patients with those and other diseases. Additional studies give new insight into best practices for the treatment of various blood cancers.