City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.
April 4, 2017 | Katie Neith
Yanhong Shi, Ph.D., professor and director of the Division of Stem Cell Biology Research at Beckman Research Institute of City of Hope, believes she and colleagues have found a way to suppress the growth and self-renewal in a certain type of cancer stem cell.
March 29, 2017 | Katie Neith
Prostate cancer is the third leading cancer killer among men. Now, a team from City of Hope believes they have found a key mechanism for potentially keeping the disease at bay, both before and after diagnosis.
March 14, 2017 | Katie Neith
A paper published in the Feb. 13 issue of the journal Nature points to increased glucose as the driver of the energy needed for specific cells to transform into malignant cancer cells.
March 6, 2017 | Denise Heady
Researchers have designed a method to engineer Car-T cells with something called a "reporter" gene, so they can be tracked and monitored by scientists once they are injected into a patient’s brain.
March 1, 2017 | Katie Neith
A clinical trial monitored by Bart Roep, Ph.D., showed promising results for a possible cure of type 1 diabetes (T1D). The study identified new paths for personalized therapies of T1D.
February 28, 2017 | Jyoti Madhusoodanan
Coupled with new drugs that target tumor-specific genomic changes, next-generation sequencing (NGS) tests have the potential to transform modern cancer care.
February 1, 2017 | Letisia Marquez
Alex F. Herrera, M.D. and a team of doctors from City of Hope and the Dana-Farber Cancer Institute examined how patients whose double-hit and/or double-expressor lymphoma had recurred, or was resistant to initial treatment, fared after undergoing high-dose chemo and stem cell transplantation.
January 9, 2017 | Abe Rosenberg
Everything changed when Hodgkin lymphoma patient Lowell Winer joined a Phase II clinical trial examining the effectiveness of brentuximab vedotin (BV) after a failed transplant. The BV worked immediately, achieving a complete remission which, year after year, proved to be durable beyond anyone's expectations.
December 8, 2016 | Samantha Bonar
City of Hope patient Susan Young - diagnosed with late-stage triple negative breast cancer - has had a remarkable response to a revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding protein.
December 7, 2016 | City of Hope
Numerous clinical trials, which lay the groundwork for novel approaches to lymphoma and multiple myeloma therapies, could ultimately lead to new treatments that improve survival and quality of life for patients with those and other diseases. Additional studies give new insight into best practices for the treatment of various blood cancers.