Building Better Antibodies with John Williams, Ph.D.

April 19, 2018 | Katie Neith

Researchers at Beckman Research Institute of City of Hope use novel technology to add new functionalities to already potent proteins.

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New Study: Bifunctional JMDJ1B gene controls cell fate decision of blood progenitors

May 23, 2018 | Samantha Bonar

Diseases like cancer arise due to both changes in gene expression and cellular function. One important factor regulating gene expression and cellular function is called epigenetic modifications. Epigenetic modifications are inheritable changes not associated with changes in the DNA sequence.

City of Hope's CEACAM Research Comes Full Circle with New CAR T Approach

February 9, 2018 | Jyoti Madhusoodanan

More than 50 years after its discovery, CEA remains one of the most widely used clinical markers of cancer. As the diverse roles of CEA and its family members, known as CEA-related cell adhesion molecules (CEACAMs), have grown clearer, researchers at City of Hope are working on a new wave of clinical tools and therapies.

New Biomarker Link in Nonsmall Cell Lung Cancer Discovered

January 12, 2018 | Elise Lamar

Ravi Salgia, M.D., Ph.D., recently published in Scientific Reports about a novel and promising link between two NSCLC biomarkers. The study might help oncologists match patients with effective drug interventions against specific forms of NSCLC.

Relapsed Hodgkin Lymphoma Effectively Treated with Immunotherapy

January 7, 2018 | Katie Neith

Researchers led by Alex Herrera, M.D. have found that a combination of two immunotherapy drugs may be a more tolerable way for patients to fight the disease before a transplant.

City of Hope Physicians Announce CAR T Cell Breakthroughs at ASH

January 6, 2018 | Letisia Marquez

New blood cancer breakthroughs – including several involving CAR T cell therapy – were announced by City of Hope physicians at the American Society of Hematology (ASH) annual meeting in Atlanta.

City of Hope's Alpha Clinic Creates a New Nursing Role

January 3, 2018 | Wayne Lewis

According to a new paper in Stem Cells Translational Medicine, the authors identify the role of a nurse qualified in both patient care and research protocols, the so-called “hybrid nurse” — a homegrown City of Hope innovation — as an important component of their success in the development of the Alpha Clinic.

Weight Loss May Lower Your Risk of Developing Breast Cancer

January 2, 2018 | City of Hope

Postmenopausal women who lose weight may have a significantly reduced chance of developing breast cancer, according to data presented by City of Hope’s Rowan Chlebowski, M.D., Ph.D., at the 2017 San Antonio Breast Cancer Symposium.

New Study Tracks Treatment Resistance in Metastatic Breast Cancer

November 9, 2017 | City of Hope

Findings from a new study provide fresh insights into the treatment of women with metastatic breast cancer whose tumors are no longer responding to available treatments.