Researchers achieve remission using CAR-T Cell therapy for aggressive brain tumors

February 15, 2017 | Denise Heady

City of Hope case study published in the New England Journal of Medicine reported treatment with reengineered CAR-T cells dramatically improved quality of life for patient with recurrent glioblastoma.

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Behnam Badie given $2.1 million R01 grant to study RAGE

May 3, 2017 | Denise Heady

What started as an unplanned lunch date has turned into a potential breakthrough in the treatment of gliomas – a fast-growing, and often deadly type of brain tumor.

City of Hope Partners with Scripps to Find New Treatment for HIV

May 2, 2017 | Michael Easterling

A team from The Scripps Research Institute (TSRI) in La Jolla, California, is working with City of Hope’s Center for Gene Therapy to test a cell culture resistant to the HIV virus for efficacy and safety. If testing goes as planned, TSRI and City of Hope investigators may have identified a new treatment for HIV.

TGen Identifies Promising New Compound for Treatment of Glioblastoma

April 20, 2017 | City of Hope

A study led by scientists at the Translational Genomics Research Institute (TGen) has identified a chemical compound called Aurintricarboxylic Acid (ATA), shown to block the chemical cascade that otherwise allows glioblastoma cells to resist both chemo and radiation therapy.

Experts Discuss Advancements in Stem Cell Therapies at Second Annual Meeting

March 29, 2017 | Michael Easterling

The stories of patients who have benefited from stem cell therapies funded by the California Institute for Regenerative Medicine (CIRM) were the focus of the second symposium of the institute’s Alpha Stem Cell Clinics Network.

City of Hope and TGen Join Forces to Advance Precision Medicine

December 2, 2016 | City of Hope

City of Hope is joining forces with the Translational Genomics Research Institute (TGen) to accelerate the speed with which scientists and medical staff can convert research discoveries into cures for patients.

Collaboration leads to new pathway to increase drug sensitivity

October 19, 2016 | Katie Neith

Science doesn’t always start in the lab. Sometimes collaborations come together over cocktails in Costa Rica. This is how City of Hope cancer biologist Mei Kong Ph.D., and Caltech neuroscientist Viviana Gradinaru, Ph.D., started a project that could change the approach to killing cancerous tumors.

New screening tool being developed for childhood cancer survivors at risk for cardiac complications

October 6, 2016 | Katie Neith

City of Hope's Saro Armenian, D.O., M.P.H. and Caltech research Morteza Gharib, Ph.D., have helped develop a simple tool that can screen childhood cancer patients —along with other at-risk populations— for early indicators of heart disease without having to return to their oncologist.