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Breakthroughs Blog Old

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

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Core connection: Nuclear Magnetic Resonance (NMR) Core

June 20, 2019 | Katie Neith

High-resolution nuclear magnetic resonance (NMR) spectroscopy can characterize the structure, dynamics, reaction state and chemical environment of biomolecules.

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Categories : Innovation

breakthroughs - arthur riggs legacy

40-year Anniversary of Landmark Paper that Led to Synthetic Insulin

February 21, 2019 | Michael Easterling

In January 1979, the National Academy of Sciences published a paper about an innovative discovery at City of Hope that would forever change how diabetes is treated.

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Categories : Innovation

Orange cells

Coaxing Alpha Cells to Produce Insulin

February 21, 2019 | Katie Neith

A paper co-authored by Bart Roep, Ph.D., Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and the founding chair of the Department of Diabetes Immunology at City of Hope, published in Nature explores new ways of replacing beta cells after too many of them have been killed by the immune system.

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Lauren Lugo | City of Hope

An Engineer Tackles CAR T Cell Therapy

February 18, 2019 | City of Hope

Vanessa Jonsson, Ph.D., has solved tough problems for the Aquarius Mission at NASA’s Jet Propulsion Laboratory and helped design autonomous cars for the Defense Department’s DARPA program. Now, she's taking on cancer.

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Categories : Innovation


City of Hope scientist's stem cell model could be key to slowing Alzheimer's

September 28, 2018 | Zen Vuong

Treatments for a rare nervous system disorder and, eventually, Alzheimer's disease could be influenced by new research conducted by City of Hope's Yanhong Shi, Ph.D.

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Saswatee Chatterjee

New Genome-Editing Platform Poised To Fuel The Next Generation Of Genetic Medicines

July 17, 2018 | Zen Vuong

A novel gene-editing tool discovered at City of Hope has the potential to treat a variety of genetic diseases.

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Categories : Innovation

Electron_Microscopy | City of Hope

Core Connection: Light Microscopy and Digital Imaging

May 23, 2018 | Katie Neith

Microscopes have been the backbone of many scientific experiments since at least the 1600s, but as technology rapidly progresses, these instruments become more complex and harder to use. Nonetheless, microscopes, paired with advanced digital imaging techniques, remain critical tools for biomedical research, disease diagnostics and in tracking the body’s response to treatment therapies. They are also necessary for producing quality images for journal submissions and grant proposals.

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Categories : Innovation


Test Finds Promising New Drug to Treat Chronic Myelogenous Leukemia

May 15, 2018 | Katie Neith

City of Hope researchers may have discovered a more effective treatment for patients with chronic myelogenous leukemia (CML) according to a study published today in Nature Medicine.

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Sickle cell anemia | City of Hope

CIRM Grants Nearly $6M to Promising Sickle Cell Research

May 15, 2018 | Michael Easterling

City of Hope’s Joseph Rosenthal, M.D., and his team can advance their research into finding a cure for sickle cell disease, thanks to a $5.74 million award from the California Institute for Regenerative Medicine.

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Haiyong Han TGen | City of Hope

TGen Tests Ultrasound to Enhance Drug Delivery in Cancer Therapy

May 15, 2018 | City of Hope

TGen (a City of Hope affiliate) has teamed up with a Norwegian biotech company to test the use of ultrasounds to direct and focus cancer drug therapies.

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Categories : Innovation

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