New drug shows strong results against stubborn mutation

June 5, 2019 | Michael Easterling

A new drug being investigated by Marwan Fakih, M.D., professor in the Department of Medical Oncology & Therapeutics Research and medical director of the Judy & Bernard Briskin Center for Clinical Research, is "potentially practice-changing," Fakih said.

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Core connection: Nuclear Magnetic Resonance (NMR) Core

June 20, 2019 | Katie Neith

High-resolution nuclear magnetic resonance (NMR) spectroscopy can characterize the structure, dynamics, reaction state and chemical environment of biomolecules.

40-year Anniversary of Landmark Paper that Led to Synthetic Insulin

February 21, 2019 | Michael Easterling

In January 1979, the National Academy of Sciences published a paper about an innovative discovery at City of Hope that would forever change how diabetes is treated.

Coaxing Alpha Cells to Produce Insulin

February 21, 2019 | Katie Neith

A paper co-authored by Bart Roep, Ph.D., Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and the founding chair of the Department of Diabetes Immunology at City of Hope, published in Nature explores new ways of replacing beta cells after too many of them have been killed by the immune system.

An Engineer Tackles CAR T Cell Therapy

February 18, 2019 | City of Hope

Vanessa Jonsson, Ph.D., has solved tough problems for the Aquarius Mission at NASA’s Jet Propulsion Laboratory and helped design autonomous cars for the Defense Department’s DARPA program. Now, she's taking on cancer.

City of Hope scientist's stem cell model could be key to slowing Alzheimer's

September 28, 2018 | Zen Vuong

Treatments for a rare nervous system disorder and, eventually, Alzheimer's disease could be influenced by new research conducted by City of Hope's Yanhong Shi, Ph.D.

New Genome-Editing Platform Poised To Fuel The Next Generation Of Genetic Medicines

July 17, 2018 | Zen Vuong

A novel gene-editing tool discovered at City of Hope has the potential to treat a variety of genetic diseases.

Core Connection: Light Microscopy and Digital Imaging

May 23, 2018 | Katie Neith

Microscopes have been the backbone of many scientific experiments since at least the 1600s, but as technology rapidly progresses, these instruments become more complex and harder to use. Nonetheless, microscopes, paired with advanced digital imaging techniques, remain critical tools for biomedical research, disease diagnostics and in tracking the body’s response to treatment therapies. They are also necessary for producing quality images for journal submissions and grant proposals.

Test Finds Promising New Drug to Treat Chronic Myelogenous Leukemia

May 15, 2018 | Katie Neith

City of Hope researchers may have discovered a more effective treatment for patients with chronic myelogenous leukemia (CML) according to a study published today in Nature Medicine.