Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

breakthroughs - Behnam Badie and Christine Brown
City of Hope researchers find CAR-T cell therapy effective in treatment of glioblastoma

July 17, 2018 | Denise Heady

City of Hope researchers have found that using CAR-T therapy, a type of immunotherapy, can be effective in the treatment of glioblastoma — one of the most aggressive brain tumors known to medicine.

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Breakthroughs - brain tumors and cancer - what you need to know - 256x256
Brain tumors and cancer: what you need to know

July 18, 2017 | Denise Heady

Say the words “brain tumor” and most people will likely think of cancer. But the truth is, having a brain tumor doesn’t always lead to a cancer diagnosis.

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George Hajjar Bio Photo
Targeted Therapy 101: A Primer

July 17, 2017 | City of Hope

Cancer care has come a long way. Surgery, chemotherapy and radiation have traditionally been the three pillars of cancer care, and they are still important treatments. But in recent years, newer “targeted therapies” have come on the scene.

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Joe Gold, Manufacturing Director, Center for Biomedicine and Genetics, City of Hope
Joe Gold: Stem Cell Champion

July 13, 2017 | Abe Rosenberg

Joseph Gold, Ph.D., is chief overseer of a sprawling, state-of-the-art manufacturing facility cranking out mass quantities of carefully engineered stem cells aimed at curing the most dangerous and debilitating diseases of our time.

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researcher in the lab
City of Hope collaborates with The Jackson Laboratory to help speed research discoveries into cures

July 11, 2017 | Denise Heady

A collaboration with The Jackson Laboratory expands access to leading-edge research capabilities to find new treatments for life-threatening diseases.

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breakthroughs - wanek gift
City of Hope Aims to Cure Type 1 Diabetes in Six Years

July 11, 2017 | City of Hope

City of Hope’s Diabetes & Metabolism Research Institute is committed to developing a cure for type 1 diabetes within six years, fueled by a $50 million funding program led by the Wanek family.

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breakthroughs - cancer cells
Researchers discover sugar-addiction of cancer cells in childhood leukemia

July 10, 2017 | Katie Neith

According to a new article in Nature, a team led by City of Hope’s Markus Müschen, M.D., Ph.D., Chair of the Department of Systems Biology, thinks that sugar uptake and energy supply may play a key role in the relapse of ALL.

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CAR T Illuminated
CAR-T cells: ‘Soldiers of the Immune System’

July 10, 2017 | Stephanie Smith

When viewed under a microscope, T cells - sentinels of the immune system whose job inside the body is to seek out foreign invaders - quiver as they surround and consume cancer cells. They were genetically modified in a lab by City of Hope researchers and trained to target specific receptors on patients’ brain tumors - part of an emerging approach to cancer care called immunotherapy.

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patel sunita 256x256
City of Hope Researcher Receives Grant to Improve Cognitive Outcomes in Young Cancer Patients

July 7, 2017 | Samantha Bonar

Sunita Patel, Ph.D., a neuropsychologist in the Population Sciences and Supportive Care Medicine departments at City of Hope, has received a $1.22 million grant from the American Cancer Society to test a new approach toward preventing long-term chemotherapy-related cognitive side effects in childhood cancer survivors from bilingual and Spanish-speaking families.

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Markus Muschen
The Search for the Elephant Gene

July 5, 2017 | Michael Easterling

The African bull elephant is the largest mammal on the planet, comprised of trillions of cells that should ostensibly be a breeding ground for cancer. But because of an evolutionary anomaly, elephants don’t get cancer, a fact that fascinates Markus Müschen, M.D., Ph.D.

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