Breakthroughs Blog

City of Hope has so many breakthroughs in cancer, diabetes and HIV/AIDS - and so many stories - that we've tailored our blog, Breakthroughs, to provide something for every reader. Whether the breakthroughs are about medical research, treatment advances or personal triumphs, they're all connected.

Meet our doctors: How Leo Wang is revolutionizing the way that pediatric and blood cancers are treated

March 17, 2017 | Denise Heady

Dual-trained pediatric oncologist and scientist Leo Wang, M.D., Ph.D., is working in the lab to understand how blood cells develop and grow, and plans to use that information to help patients with cancer live longer and experience fewer side effects of treatment.

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Wolf in sheep's clothing: breast cancer cloaks itself in brain proteins to invade the brain

March 14, 2017 | Denise Heady

More women than ever are surviving breast cancer only to die of secondary brain tumors years after they’ve been declared cancer-free. This is particularly true for patients with the breast cancer subtype HER2-positive. Now City of Hope researchers have discovered how this happens.

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Inside the California Teachers Study: The Future

March 8, 2017 | Stephanie Smith

The California Teachers Study, a more than two-decade long study of more than 133,000 teachers, started in 1994. James Lacey, Ph.D., who now runs the study, wants to pool data from this and other studies to create a personalized prevention tool.

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Inside the California Teachers Study: The Disruptor

March 6, 2017 | Stephanie Smith

The California Teachers Study, a more than two-decade long study of more than 133,000 teachers, started in 1994. James Lacey, Ph.D., who now runs the study, is taking on the role of disruptor, as he transforms how study data is collected and shared.

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Inside the California Teachers Study: The Teachers

March 4, 2017 | Stephanie Smith

The California Teachers Study, a more than two-decade long study of more than 133,000 teachers, started in 1994. Bridget Marshall, a former patient and current employee at City of Hope, one of the centers out of which the study is run, also has been a participant in the California Teachers Study for more than two decades.

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Inside the California Teachers Study: The Finding

March 2, 2017 | Stephanie Smith

The California Teachers Study, a more than two-decade long study of more than 133,000 teachers, started in 1994. Just before the study started, Leslie Bernstein, a researcher at City of Hope cancer center, was making a big splash in breast cancer research.

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Stem Cell Transplants Lead to Cure for Some Type 1 Diabetes Patients

March 1, 2017 | Katie Neith

A recent clinical trial monitored by City of Hope’s Bart Roep, Ph.D., showed promising results for a possible cure of type 1 diabetes (T1D). Although the study involved risky stem cell transplant procedures, it identified new paths for personalized therapies of T1D.

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Inside the California Teachers Study: The Statistician

March 1, 2017 | Stephanie Smith

The California Teachers Study, a more than two-decade long study of more than 133,000 teachers, started in 1994, but its eventual principle investigator, Leslie Bernstein of City of Hope, was dreaming about making her mark -- and making a difference -- long before then.

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New Study Flips the Script on Cause of Type 1 Diabetes

February 27, 2017 | Katie Neith

For decades, scientists believed that the root cause of type 1 diabetes (T1D) was the immune system mistakenly identifying insulin secreting beta cells as a potential danger and, in turn, destroying them. Now, a study led by City of Hope’s Bart Roep turns that idea on its head.

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Liquid Biopsy Offers a New Way to Target Kidney Cancer

February 17, 2017 | Denise Heady

Despite a wave of new targeted therapies being approved to treat kidney cancer, many of those therapies have been challenging to use because of the difficulty in obtaining cancer tissue for genomic testing. Now, researchers may have found a way to combat this problem: the liquid biopsy.

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