15,000 second chances: Bone Marrow Transplant program celebrates new milestone

April 24, 2019 | Michael Easterling and Samantha Bonar

City of Hope’s bone marrow transplant program recently performed the procedure on its 15,000th patient, a remarkable milestone considering that the initiative started with just two physicians, three beds and guarded expectations in 1976.

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Will CAR T be the answer for amyloidosis?

May 21, 2019 | Maxine Nunes

A City of Hope scientist believes the solution to the rare disease amyloidosis may be found in one of the most exciting new frontiers of immunotherapy, chimeric antigen receptor T cell therapy.

Probiotic may suppress fatal brain inflammation

May 14, 2019 | Zen Vuong

The existence of certain microorganisms in your gut may bolster the immune system’s ability to fend off a herpes viral attack that can cause fatal brain inflammation, reports a new City of Hope-led study.

Bold steps toward a cure: Clinical trials at City of Hope

May 3, 2019 | Abe Rosenberg

City of Hope’s clinical trials program is special because it was built with the same core values as the institution itself: an emphasis on leading-edge medicine, compassionate care, rapid bench-to-bedside research and always putting the patient first.

Scientists gaining on graft-versus-host disease

May 2, 2019 | Abe Rosenberg

Scientist Defu Zeng is tackling graft-versus-host disease, a common side effect of bone marrow transplants, taking several tacks that include modulating T cells and fine-tuning specific proteins and antibodies.

Colorectal tumor biomarker may predict immunotherapy effectiveness

May 2, 2019 | Zen Vuong

The takeaway of foundational research by a City of Hope physician-scientist and his colleagues is that patients with metastatic colorectal cancer and a high tumor mutation score should consider immunotherapy as initial treatment.

John Rossi, Ph.D., receives highest honor from American Society of Gene and Cell Therapy

April 29, 2019 | Michael Easterling

John Rossi, Ph.D., the Lidow Family Research Chair and professor of the Department of Molecular and Cellular Biology, is the recipient of the 2019 Outstanding Achievement Award presented by the American Society of Gene and Cell Therapy.

International diabetes experts converge for Levine-Riggs symposium

April 23, 2019 | Michael Easterling

More than 250 physicians and scientists from around the world attended the 2019 City of Hope Levine-Riggs Diabetes Research Symposium, held April 10 to 13 at The Westin Hotel in Pasadena, California.

Exercise Lowers Heart Disease Risk in Breast Cancer Patients

April 23, 2019 | Letisia Marquez

After taking part in a 16-week exercise intervention, women who had early-stage breast cancer, and who were also inactive and overweight or obese, had a lower risk of developing cardiovascular disease, according to a new study in JAMA Oncology.

TGen IDs gene associated with most common liver cancer

April 19, 2019 | City of Hope

AKR1B10 could help provide early detection of hepatocellular carcinoma, and play a role in monitoring and treating this growing cause of cancer death.

Combined immunotherapy could tackle advanced cancers

April 15, 2019 | Zen Vuong

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly impossible-to-treat cancer into a disease that can be corralled into remission.