Meet the Newest City of Hope Researchers
April 5, 2017 | by City of Hope
Anne Reb, Ph.D.: Anne M. Reb, Ph.D., has joined City of Hope as assistant professor in the Division of Nursing Research and Education within the Department of Population Sciences. Reb has experience with quantitative, qualitative and mixed methods research studies. She is currently an associate investigator on a feasibility study of a nurse-led GYN Oncology Survivorship Program at a military treatment facility. She has served as principal investigator on a feasibility study of Mantram Repetition in Women with Advanced Ovarian Cancer, and on a qualitative study describing the experience of hope in women with advanced ovarian cancer, and the significance of high support, control and communication among this population. Reb has published in the areas of cancer screening, mind-body interventions in the rehabilitation setting, palliative care, and the care of the older adult with cancer. She has been a mentor to researchers and graduate students regarding study design issues, protocol development and study implementation.
Lei Jiang, Ph.D.: Lei Jiang, Ph.D., has joined the Diabetes & Metabolism Research Institute as an assistant professor in the Department of Molecular and Cellular Endocrinology. Jiang comes to City of Hope after his postdoctoral training at The University of Texas Southwestern Medical Center, where he studied cancer metabolism in the Children's Medical Center Research Institute.
Jiang completed his Ph.D. in biochemistry and molecular biology from the Institute for Nutritional Science, Shanghai Institutes for Biological Sciences, part of the Chinese Academy of Sciences. He received the Chinese Academy of Sciences Dean Award and Unilever Scholarship, and he was also honored as the Merit student of Chinese Academy of Sciences.
During his research training, Jiang has had several high-profile publications as first author (in Nature, Proceedings of the National Academy of Sciences, Journal of Hepatology and Oncogene) and co-author, and more recently as a co-corresponding author for the journal of Metabolic Engineering).
Intellectually curious, Jiang will be concentrating on the molecular mechanisms regulating nutrient homeostasis during the development and progress of metabolic diseases, such as diabetes and cancer. His research will particularly focus on the novel alteration of central carbon metabolism (glycolysis and oxidative phosphorylation) under pathological conditions, through the application of the cutting edge mass spectrometry-based metabolic tracing and systemic bioengineering.
Jiang says he is looking forward to collaborating with new colleagues in the areas of diabetes and cancer. He is also looking forward to mentoring the next generation of scientists.
Qiong (Annabel) Wang, Ph.D.: Qiong Wang, Ph.D., has joined the Diabetes & Metabolism Research Institute as an assistant professor in the Department of Molecular and Cellular Endocrinology. Wang comes to City of Hope after her postdoctoral training in the lab of Philipp Scherer, Ph.D., at the Touchstone Diabetes Center of The University of Texas Southwestern Medical Center, where she studied adipose tissue physiology.
Wang’s postdoctoral research in tracking adipogenesis during adipose tissue development and remodeling was supported by an American Diabetes Association mentor-based postdoctoral fellowship award. She is currently funded by a K01 career development award from the National Institute of Diabetes and Digestive and Kidney Diseases.
Wang completed her Ph.D. in biochemistry and molecular biology in the laboratory of Dr. Yong Liu, from the Institute for Nutritional Science, Shanghai Institutes for Biological Sciences, the Graduate School of Chinese Academy of Sciences. Her graduate study focused on identifying novel targets in the liver for the treatment of obesity and insulin resistance. During her graduate training, she received numerous awards, including the Chinese Academy of Sciences Dean Award.
She has first-authored papers in the journals Nature Medicine, Nature Cell Biology, Hepatology, Molecular Metabolism, and the Journal of Lipid Research. She has served as a reviewer for journals such as Endocrinology, the Journal of Biological Chemistry, Molecular Endocrinology and Cancer & Metabolism.
In her research, Wang’s is interested in the region-specific remodeling of adipose tissue, both in physiological and pathological conditions, such as insulin resistance and obesity. Her lab here is currently working on two transformative projects in fulfillment of our mission to turn science into practical benefit: 1) white adipose tissue remodeling in the mammary gland during pregnancy, lactation, and involution, 2) brown adipose tissue heterogeneity, and how this heterogeneity regulates the energy burning activity of brown adipocytes.
Wang says she is looking forward to collaborating with new colleagues at the City of Hope in the area of diabetes, cancer and beyond. She also has great enthusiasm in mentoring the next generation of scientists.
Markus Müschen, M.D., Ph.D.: Markus Müschen, M.D., Ph.D., has joined City of Hope as the Norman and Sadie Lee Foundation Professor in Pediatrics, and founding chair of the Department of Systems Biology, a division of Beckman Research Institute of City of Hope. Müschen will serve as new associate director of Pediatric Oncology in City of Hope's National Cancer Institute-designated comprehensive cancer center.
Müschen was previously a tenured Professor of Laboratory Medicine, Pathology and Medicine at the University of California San Francisco (UCSF). Since 2010, he served as program leader of the Hematological Malignancies Program of the UCSF Comprehensive Cancer Center. Müschen is a Howard Hughes Medical Institute (HHMI) Faculty Scholar and is supported by an NCI ‘Outstanding Investigator Award’ (R35).
He received his medical degree from the Heinrich-Heine-Universität in Düsseldorf, Germany, where he graduated summa cum laude. He completed his medical training in hematology-oncology in Cologne, under Volker Diehl.
After scientific training experiences at the Institut Pasteur in Paris, in Klaus Rajewsky’s laboratory at the Institute of Genetics in Cologne and Janet Rowley’s laboratory at the University of Chicago, Müschen launched his own independent laboratory in 2001 in Cologne. In 2006, he moved with his entire group to the University of Southern California to build a translational research program as leader of the Leukemia and Lymphoma Program of the USC Norris Comprehensive Cancer Center and Children’s Hospital Los Angeles.
Müschen received a Scholar Award from the Leukemia & Lymphoma Society, a Stand Up to Cancer Innovation Award from the American Association for Cancer Research, a Senior Investigator Award from the Wellcome Trust and held the 2012 Sir Alexander Haddow Professorship of the Institute of Cancer Research in London.