Irell and Manella Graduate School of Biological Sciences at City of Hope National Medical Center Quarterly Newsletter: January through March 2015

April 27, 2015 | by City of Hope

HelixStaffAnnouncements

Congratulations to Jodi Murakami and her fiancée, who welcomed home their baby boy in December.

 

Congratulations to Nathaniel Magilnick and his wife, who welcomed home their baby boy in March.

 

Congratulations to first-year students Alexandra Ciminera, Michelle Ho, John Murad, Manbir Sandhu, and Dongrui Wang, the recipients of the H.N. & Frances Berger Foundation Fellowship based on their academic performance in the fall classes.

 

Leading-Edge Lectures

The Leading-Edge Lecture series is sponsored by the City of Hope Graduate School students. For each Lecture, a student invites an outstanding biomedical scientist to present a research seminar. Before the seminar, the student also gives a presentation and leads a discussion about the research topic of his or her invited speaker.

 

January:

Chun-Ting (Isaac) Cheng (Laboratory of David Ann) sponsored David C. Chan, PhD, whose talk was entitled “Physiological functions of mitochondrial dynamics.”

 

Graduate Student Forum

The Graduate Student Forum comprises research talks by graduate students to faculty and fellow students in order to enrich the graduate training experience.

 

January:

Sangeetha Satheesan (Laboratory of John Rossi) presented “Development and Characterization of the NSG mouse model to test anti-HIV constructs and establish viral latency”

Richard Jaramillo (Laboratory of John Termini) presented “N2-(1-carboxyethyl)-2’-deoxyguanosine (CEdG) is elevated in a mouse model of diabetes and correlates with fasting plasma glucose and HbA1C

 

March:

Chao Wang (Laboratory of John Chan) presented “The Role of IDH2R172 Mutations in the Pathogenesis of Angioimmunoblastic T-cell Lymphoma”

Hubert Li (Laboratory of Nagarajan Vaidehi) presented “A Computational Method to Identify Druggable Binding Sites That Target Protein-Protein Interactions”

 

Student Publications

These students were credited as authors in research articles that were published during this quarter.

 

Manasa Chandra (Laboratory of Saswati Chatterjee): Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Andrew Chin (Laboratory of Emily Wang): Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

James Finlay (Laboratory of Carlotta Glackin): RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis

Sean Howard (Laboratory of Jeremy Stark): DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining

Bei Jiang (Laboratory of John Chan): Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

Michael Reid (Laboratory of Mei Kong): The Histone Demethylase Jumonji Coordinates Cellular Senescence Including Secretion of Neural Stem Cell-attracting Cytokines and Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Cai Roberts (Laboratory of Carlotta Glackin): RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis

Sangeetha Satheesan (Laboratory of John Rossi): Cell-Specific RNA Aptamer against Human CCR5 Specifically Targets HIV-1 Susceptible Cells and Inhibits HIV-1 Infectivity

Jacob Tremblay (Laboratory of Teresa Ku): Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Xichun (Steve) Wang: Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3 and Bile acid signaling and liver regeneration

 

New Graduate Student Organization (GSO) Officers

In February, the student body elected new officers for 6 month- or year-long terms.

President: Sean Howard

Secretary: Ragini Bhargava

LEL Coordinator: Ethan White

Social Chair: Megan Minnix

 

Social Events

January:

Ice Skating at Pasadena Ice Skating Center

Beckman Pub

 

February:

Valentine’s Day-themed Beckman Pub

 

March:

Boardgame Night at Game Haus Cafe

St. Patrick’s Day-themed Beckman Pub

 

Other Events

  • First-year graduate students finish second and third rotation projects
  • The graduate school held interviews and accepted 17 students for the 2015-2016 incoming class
 

Jacob Tremblay shares his experience as Co-Recruitment Chair:

 

New faces, new names, and a whole lot of nervous laughter. It must have been recruitment season again! Recruitment has always meant a good time for those who volunteer and get to interact with so many brilliant applicants, but as recruitment chairs we see a little bit of a different side. We see stress, and rattled nerves, and we ourselves fret out over the planning and execution. Three whole weeks of the culmination of planning, sweating, and praying to God that everything works out alright. Sounds like a pain, right? Well this is my second year being a Recruitment Co-Chair and let me say if any one thing rings true after each recruitment season, it’s that when the last interviewees leave to go home, I miss it. The laughing and talking and getting to know everyone is always a thrill. Even the stress and pressure is rewarded at the end of it all when we were able to make a difference in the grad school by accepting 17 new and fantastic graduate students. One thing is for sure— I definitely look forward to volunteering with recruitment for the rest of my time here!

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