Laura Kruper, 醫學博士、理學碩士

  • Rita Cooper Finkel 和 J. William Finkel 婦女健康中心主任
  • 乳癌服務主任
  • 乳癌科聯合主任
  • 外科副教授
  • 腫瘤外科醫師

Laura Kruper, 醫學博士、理學碩士

研究重點 :
  • 乳癌
臨床專業領域
  • 手術腫瘤科
  • 乳腺手術
專業領域
  • 保乳手術
  •  
  • 乳癌

「每位患者都有不同的故事。 我的目標是根據病患的疾病階段、個人價值觀及其家族史為每位乳癌病患提供幾個治療選擇。」 

Laura L. Kruper 醫學博士曾領導一項重大研究,研究發現在 10 位接受乳房切除術的女性中有 7 位沒有進行重建手術。 她想改變這種狀況,尤其是在聽到她的低收入弱勢病患在其他醫院拒絕為這些患者進行重建手術後。

她表示「我的一個目標是讓每個人都能得到更平等的對待。」

Kruper 醫生畢業於賓州大學醫學院畢業,有超過 15 年的癌症外科經驗。 自 2008 年起,她在City of Hope努力透過臨床試驗來改善乳腺癌的治療,以儘快為病患提供最好的治療。

作為在電視新聞和訪談節目很受歡迎的醫學專家,Kruper 醫生熱衷於提高人們的乳腺癌意識和加強教育。

  • 2012年迄今,加州City of Hope Duarte 院區乳癌科Cooper Finkel 女性健康中心主任暨共聯合主任
  • 2008年迄今,加州City of Hope Duarte 院區外科腫瘤外科分部助理教授暨外科醫師
  • 1999年,賓州大學醫學院解剖生理學系助教
  • 1995-1996年,賓州費城賓州大學 Wistar 研究院研究助理
  • 1995年Bryn Mawr大學化學系助教
  • 1990-1993年紐約 Condé
  • Nast 旅遊雜誌助理相片編輯

學位

  • 2015年,史丹佛大學,史丹佛女性領導者培養計劃,加州史丹佛
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  • 2005年,賓夕法尼亞大學臨床流行病學與生物統計學中心,醫療服務與結果研究專業,理科碩士,賓夕法尼亞州費城
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  • 2000年,賓夕法尼亞大學醫學院,醫學博士,賓夕法尼亞州費城
  •  
  • 1989年,布朗大學埃及學專業,文學學士,優等生,羅得島 Providence

臨床研究醫師

  • 2007年 - 2008年,John Wayne 癌症研究所,乳腺腫瘤研究員,加州 Santa Monica
  • 查無資料

住院醫師

  • 2001年 - 2007年,賓夕法尼亞大學醫院,外科住院醫師,賓夕法尼亞州費城

實習

  • 2000年 - 2001年,耶魯大學,耶魯 New Haven 醫院,外科實習生,康乃迪克州 New Haven

我長期的學術與研究目標是透過更佳的臨床試驗來讓乳癌管理的效果發揮到最大。 我深信達到這個目標的其中一個方法,就是將基本的實驗室研究的現有科學研究轉化成臨床研究,最終成為臨床實驗。

  1. Kruper L, Low DW, Bucky LP: Immediate Pectoralis Flap Closure Following Septic Arthritis of the Manubriosternal Joint. Plast Reconstr Surg 2001;107(4):997-9
  2. Kruper L, Tchou J. The Breast. In: Kaiser LR, ed. The Surgical Review: An Integrated Basic and Clinical Science Study Guide. 2nd ed. Philadelphia: Lippincott 2005.
  3. Kruper L, Sonnad SS. Statistics and Epidemiology. In: Kaiser LR, ed. The Surgical Review: An Integrated Basic and Clinical Science Study Guide. 2nd ed. Philadelphia: Lippincott 2005
  4. Kruper L, Schuchter L. Malignant Melanoma and non-Melanoma Skin Cancer. In: Muss HB, Hunter CP, and Johnson KA, eds. Multidisciplinary Treatment and Management of Cancer in the Elderly. New York: Taylor & Francis Group 2006.
  5. Kruper L, Spitz F, Czerniecki BJ, Blackwood-Chirchir A, Elder DE, Fraker DL, Guerry D, Ming M, Schuchter LM. Gimotty PA. Predicting sentinel node status in clinical stage I/II melanoma. Cancer, 2006; 107(10):2436-45.
  6. Kruper L, Kurichi JE, Sonnad SS. Methodological quality of cost-effectiveness analyses of surgical procedures. Annals of Surgery, 2007; 245(1):147-151.
  7. Kruper L, Giuliano AE. A randomized clinical trial on sentinel lymph node biopsy versus axillary dissection: A matter of technique. Annals of Surgery, 2008; 247(2):214-216.
  8. Kruper L, Giuliano AE. Preoperative identification of the sentinel lymph node in breast cancer. Breast Diseases: A Year Book Quarterly, 2008; 19(3): 238-9.
  9. Kruper L, Giuliano AE. Breast disease. In Practical Gynecologic Oncology, ed. Berek JS, Hacker, NF. 5th edition. Williams & Wilkins, Philadelphia, 2009.
  10. Pal SK, Lau S, Kruper L, Nwoye U, Garberoglio C, Gupta RK, Paz IB, Vora L, Guzman E, Artinyan A, Somlo G. Papillary Carcinoma of the breast: An Overview. Breast Cancer Res Treat, 2010;122(3): 637-45.
  11. Kruper L, Holt A, Xu X, Duan L, Henderson K, Bernstein L, Ellenhorn J. Disparities in reconstruction rates after mastectomy: Patterns of care and factors associated with the use of breast reconstruction in Southern California. Ann Surg Oncol 2011;18:2158-65.
  12. Kounalakis N, Pezner R, Kruper L. Partial breast irradiation in a patient with bilateral breast cancers and CREST Syndrome. Brachytherapy, 2011;10:486-90.
  13. Wiatrek R, Kruper L. Sentinel lymph node biopsy indications and controversies in breast cancer. Maturitas, 2011;69:7-10.
  14. Kruper L, Xin Xin X, Henderson K, Bernstein L. Disparities in reconstruction rates after mastectomy for ductal carcinoma in situ (DCIS): Patterns of care and factors associated with the use of breast reconstruction for DCIS as compared to invasive cancer. Ann Surg Oncol 2011;18:3210-9.
  15. Pal SK, Dehaven M, Nelson RA, Onami S, Waliany S, Hsu J, Kruper L, Mortimer J.
    Impact of modern chemotherapy on the survival of women presenting with de novo metastatic breast cancer. BMC Cancer,2012;12:435.
  16. Oxner CR, Vora L, Yim J, Kruper L, Ellenhorn JDI. Magnetic resonance-guided breast biopsy in lesions not visualized by mammogram or ultrasound. Am Surg, 2012;78:1087-90.
  17. Kruper L, Henderson K, Xu X, Bernstein L, Chen S. Utilization of mastectomy and reconstruction in the outpatient setting. Ann of Surg Oncol, 2013;20:828-35.
  18. Priceman SJ, Kujawski M, Shen S, Cherryholmes GA, Lee H, Zhang C, Kruper L, Mortimer J, Jove R, Riggs AD, Yu H. Regulation of adipose tissue T cell subset by stat3 is crucial for diet-induced obesity ad insulin resistance. Proc Natl Acad Sci 2013;110:13079-13084.
  19. Arrington A, Kruper L, Vito C, Yim JH, Kim J, Chen SL. Rural and urban disparities in the evolution of sentinel node utilization in breast cancer. Am J Surg 2013;206:674-81.
  20. Arrington A, Nelson R, Chen S, Vito C, Yim J, Kruper L. The Decision to Undergo Prophylactic Mastectomy and Subsequent Satisfaction: The patient perspective. Ann Surg Oncol. (Under Revision)
  21. Uyeno LA, Goldstein L, Chen SL, Yim JH, Kruper L. Hospital readmissions and post-operative complications following outpatient mastectomy.  (Submitted)
  22. Arrington A, Goldstein L, Kruper L, Vito C, Yim JH, Chen SL. Life expectancy after curative-intent treatment of breast cancer: Impact on long-term follow-up care.  Am J Surg  2014;80:604-9.
  23. Kruper L, Kauffmann R, Smith D, Nelson R. Survival analysis of contralateral prophylactic mastectomy: A question of selection bias? Ann Surg Oncol 2014;21:3448-56.
  24. Miller M, Ottesen R, Niland J, Kruper L, Chen S, Vito C. Lymph Node Ratio is a Prognostic Indicator of Overall Survival for Non-Metastatic Breast Cancer Patients after Neoadjuvant Chemotherapy. Ann Surg Oncol 2014;21:3317-23. PMID: 25059788
  25. Mortimer J, Jung J, Yuan Y, Kruper L, Stewart D, Chung S, Yu KM, Mendelsohn M, D’Apuzzo M, Tegtmeier B, Dadwal S. Skin/Nail infections with the addition of pertuzumab to trastuzumab-based chemotherapy. Breast Cancer Res Treat 2014;148:563-70.
  26. Bitz C, Clark K, Vito C, Kruper L, Ituarte PHG, Loscalzo M. Partners’ Clinic: An innovative gender strengths-based intervention for breast cancer patients and their partners immediately prior to initiating care with their treating physician. Psycho-Oncology 2015;24:355-8.
  27. Schinde AM, Zhai J, Yu KW, Frankel P, Yim JH, Luu T, Kruper L, Vito C, Shaw S, Vora NL, Kirschenbaum M, Somlo G. Pathologic complete response rates in triple-negative, HER2-positive, and hormone receptor-positive breast cancers after anthracycline-free neoadjuvant chemotherapy with carboplatin and paclitaxel with or without trastuzumab. Breast 2015;24:18-23.
  28. Kauffmann R, Bitz C, Clark K, Loscalzo M, Kruper L, Vito C. Addressing psychosocial needs of partners of breast cancer patients: a pilot program using social workers to improve communication and psychosocial support. Support Care Cancer 2015.
  29. Patel SK, Wong AL, Wong FL, Breen EC, Hurria A, Smith M, Kinjo C, Paz IB, Kruper L, Somlo G, Mortimer JE, Palomares MR, Irwin MR, Bhatia S. Inflammatory Biomarkers, Comorbidity, and Neurocognition in Women With Newly Diagnosed Breast Cancer. J Natl Cancer Inst 2015;107:1-7.
  30. Merchant S, Goldstein L, Kruper L. Patterns and trends in immediate post-mastectomy reconstruction in California: Complications and unscheduled admissions. Plast Reconstr Surg 2015;136:10-19.
  31. Falor A, Kruper L. “Atypical Ductal Hyperplasia.” The SCORE Portal. http://www.surgicalcore.org. July 2015.
  32. Lee M, Reinertsen E, McClure E, Liu S, Kruper L, Tanna N, Brian Boyd J, Granzow JW. Surgeon motivations behind the timing of breast reconstruction in patients requiring postmastectomy radiation therapy. J Plast Reconstr Aesthet Surg. 2015
  • 2009, American College of Surgeons Oncology Group
  • 2009, Southwestern Oncology Group
  • 2009, American Society of Breast Surgeons
  • 2009, American College of Surgeons, So. CA Chapter
  • 2007, Society of Surgical Oncology
  • 2001, American College of Surgeons
  • 2011年 - 2015年,Pasadena 頂級醫生
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  • 2007年,Lynn Sage 乳腺癌研究員旅行獎
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  • 2003年 - 2005年,美國國家健康研究服務獎(NRSA),賓夕法尼亞大學臨床流行病學中心
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  • 2000年,賓夕法尼亞大學醫學院 Alpha Omega Alpha 會員
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  • 1999年,美國國立衛生研究院癌症獎
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  • 1997年,美國國立衛生研究院短期研究獎
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  • 1989年,布朗校友學術卓越獎
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  • 1987年,Dorot 考古旅行獎
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