Chintan Parekh, M.B.B.S.

Chintan Parekh, M.B.B.S.
Pediatric Hematologist-Oncologist
Academic Appointments
  • Associate Professor, Department of Pediatrics

Chintan Parekh, M.B.B.S., is an associate clinical professor in the Department of Pediatrics at City of Hope® Cancer Center Duarte. He specializes in treating pediatric leukemia and conducting basic science laboratory research in the fields of T-cell immunotherapy, blood cell development and blood cancers. He chose to focus on pediatric care because of the profound impact that curing cancer has on a young person’s life.

After earning his medical degree at the Seth Gordhandas Sunderdas Medical College in Mumbai, India, Dr. Parekh did residencies in pediatrics at Swansea NHS Trust in the United Kingdom and the Women & Children’s Hospital of Buffalo (now Oishei Children's Hospital) in New York state, followed by a fellowship in pediatric hematology-oncology at Children’s Hospital Los Angeles. Prior to joining City of Hope, Dr. Parekh was an associate professor of clinical pediatrics at the Keck School of Medicine at the University of Southern California.

A board-certified pediatric hematologist-oncologist, his research is funded by R01 grants from the National Institute of Health (NIH). He has peer-reviewed publications in journals such as Immunity and Nature Immunology and has received awards for his teaching.

Location

Education & Experience

Board Certifications
  • 2007, American Board of Pediatrics, Maintenance of Certification (MOC) current
  • 2011, American Board of Pediatric Hematology Oncology (MOC) current
Degree
  • 2003, M.B.B.S., Seth G.S. Medical College, Mumbai, India
Residencies
  • 2003-2004, Residency, Pediatrics, Swansea NHS Trust, Swansea, United Kingdom
  • 2004-2007, Residency, Pediatrics, Women and Children’s Hospital of Buffalo, Buffalo, NY
Fellowship
  • 2007-2011, Fellowship, Pediatric Hematology-Oncology, Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA
Professional Experience
  • 2024-present, Associate Clinical Professor, Department of Pediatric, City of Hope, Duarte, CA
  • 2022-2024, Associate Professor, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA
  • 2012-2022, Assistant Professor, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA
  • 2011-2012, Clinical Instructor, Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA

Publications

  • Parker RS, Le J, Villa M, Luong A, Tsen YL, Lee Y,  Doan A, Aguayo-Hiraldo P, Pannaraj PS, Yeon SJ, Wallace W, Armstrong A, O'Gorman MR, Dien Bard J, Parekh C. COVID-19 vaccinated Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia show Spike Protein reactive neutralizing antibodies and/or multifunctional T-cells. . Int J Cancer. 2024 Jul 15;. doi: 10.1002/ijc.35096.
  • Parker RS, Le J, Doan A, Aguayo-Hiraldo P, Pannaraj PS, Rushing T, Malvar J, O'Gorman MR, Dien Bard J, Parekh C. COVID-19 outcomes in children, adolescents and young adults with cancer. Int J Cancer. 2022 Jul 6;. doi: 10.1002/ijc.34202. [Epub ahead of print] PubMed PMID: 35793239.
  • Gaynon PS, Parekh C. A new standard of care for childhood T-cell acute lymphoblastic leukemia?. Pediatr Blood Cancer. 2021 Oct;68(10):e29238. doi: 10.1002/pbc.29238. Epub 2021 Jul 24. PubMed PMID: 34302711.
  • Le J, Park JE, Ha VL, Luong A, Branciamore S, Rodin AS, Gogoshin G, Li F, Loh YHE, Camacho V, Patel SB, Welner RS, Parekh C. Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. Immunity. 52(6);1105-18, 2020. PMID: 32553173. PMCID: PMC7388724.
  • Gang EJ., Kim HN, Hsieh YT, Ruan Y, Ogan, HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 136(2):210-223, 2020. PMID: 32219444. PMCID: PMC7357190.
  • Ha VL, Luong A, Casero D, Li F, Malvar J, Kim YM, Bhatia R, Crooks GM, Parekh C. The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation. Leukemia. 31(11):2503–14, 2017. PMID: 28232744 PMCID: PMC5599326.
  • Moke DJ*, Oberley MJ, Bhojwani D, Parekh C** (co-last author), Orgel E**. Association of clinical trial enrollment and survival using contemporary therapy for pediatric acute lymphoblastic leukemia. Pediatric Blood and Cancer. 65(2):10.1002/pbc.26788, 2017 . PMID: 28876513 PMCID: PMC7553364. ** These authors contributed equally to this work and are co-corresponding authors.
  • Casero D, Sandoval S, Seet CS, Scholes J, Zhu Y, Ha VL, Luong A, Parekh C** (co-last author) and Crooks GM**. Global mapping and classification of long non-coding RNAs during human lymphoid commitment reveals transcriptional divergence of B and T lineages. Nature Immunology. 16(12):1282-91, 2015. PMID: 26502406 PMCID: PMC4653072. ** These authors contributed equally to this work and are co-corresponding authors.  
  • Parekh C, Gaynon PS, Abdel-Azim H. End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia. Pediatric Blood and Cancer 62(11):2040-3, 2015. PMID: 25976383 PMCID: PMC4583337.
  • Kohn LA, Hao QL, Sasidharan R, Parekh C, Ge S, Zhu Y, Mikkola HKA, Crooks GM. Lymphoid priming in human bone marrow begins before expression of CD10 with  up-Regulation of l-selectin. Nature Immunology. 13(10):963-71,2012. PMID: 22941246 PMCID: PMC3448017. 

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