City of Hope to manufacture novel cell therapies for clinical trials targeting heart, lung and blood diseases
September 22, 2016

CONTACT
Letisia Marquez
626-218-3398
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The therapies will be used in trials funded by the National Heart, Lung, and Blood Institute  

DUARTE, Calif.Beckman Research Institute of City of Hope is one of only five sites in the nation that has received a contract to manufacture novel cell therapies for heart, lung and blood diseases for use in preclinical trials.

Over the next five years, City of Hope will receive $872,000 from the National Heart, Lung, and Blood Institute (NHLBI) for administrative costs to establish a cell processing facility for production assistance for cellular therapies. City of Hope will also manufacture cell therapies for researchers nationwide who are working on new treatments for a wide range of diseases with limited options, including hemophilia, sickle cell anemia, coronary heart disease and pulmonary diseases.

The NHLBI has also established a $45 million pool for researchers nationwide to apply for services supporting the development of new cell therapies for preclinical trials. It is anticipated that City of Hope’s manufacturing will bring its total contract value to $9 million over five years.

“City of Hope is one of the premier national research facilities manufacturing biologic and chemical compounds that meet strict standards,” said Larry W. Kwak, M.D., Ph.D., the Michael Friedman Professor in Translational Medicine, vice president and associate director for translational research and developmental therapeutics at City of Hope. “Our commitment to building the best academic GMP manufacturing facilities helps us turn breakthrough discoveries into lifesaving therapies.”

Baylor College of Medicine, H. Lee Moffitt Cancer Center, University of Miami and University of Minnesota also received NHLBI contracts.

City of Hope houses three manufacturing facilities on campus that produce biologic and chemical compounds to good manufacturing practice standards. These standards follow strict U.S. Food and Drug Administration guidelines aimed at producing high quality and safe therapies for consumers.

About City of Hope
City of Hope is an independent research and treatment center for cancer, diabetes and other life-threatening diseases. Designated as one of only 47 comprehensive cancer centers, the highest recognition bestowed by the National Cancer Institute, City of Hope is also a founding member of the National Comprehensive Cancer Network, with research and treatment protocols that advance care throughout the world. City of Hope is located in Duarte, California, just northeast of Los Angeles, with community clinics throughout Southern California. It is ranked as one of "America's Best Hospitals" in cancer by U.S. News & World Report. Founded in 1913, City of Hope is a pioneer in the fields of bone marrow transplantation, diabetes and numerous breakthrough cancer drugs based on technology developed at the institution. For more information about City of Hope, follow us on Facebook, Twitter, YouTube or Instagram.
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