HopeSeq HemeFusion/Expression
HopeSeq HemeFusions/Expression (Including Acute Lymphoblastic Leukemia Ph-like Fusions)
RNAseq NGS-based assay to detect fusions in 74 genes with most possible partners (more than 3,000 selected rearrangements)
ABL1, ABL2, ALK, BCL2, BCL6, BCL11B, BCR, BIRC3, CBFB, CDK6, CCND1, CCND3, CHD1, CHIC2, CIITA, CREBBP, CRLF2, CSF1R, DEK, DUSP22, EBF1, EIF4A1, EPOR, ERG, ETV6, FGFR1, GLIS2, IKZF1, IKZF2, IKZF3, JAK2, KAT6A, KLF2, KMT2A, MALT1, MECOM, MKL1, MLF1, MLLT4, MLLT10, MYC, MYH11, NF1, NFKB2, NOTCH1, NTRK3, NUP98, NUP214, P2PR8, P2RY8, PAG1, PAX5, PBX1, PDCD1LG2, PDGFRA, PDGFRB, PICALM, PML, PRDM16, PTK2B, RARA, RBM15, ROS1, RUNX1, RUNX1T1, SEMA6A, SETD2, STIL, TAL1, TCF3, TFG, TP63, TYK2, ZCCHC7
Expression Analysis of 48 Genes
BAALC, BAX, BCL2, BCL3, BCL6, BMPR1B, CA6, CCND1, CCND2, CCND3, CD274, CD97, CDK3, CDK4, CDK6, CHN2, CRLF2, CTLA4, DNMT3B, EGFL7, EPOR, ERG, FLT1 (VEGFR1), FLT3, FLT4 (VEGFR3), FOXP1, GPR110, IGJ, IL2RA, IRF4, KDR (VEGGFR2), LMO1, LMO2, MCL1, MECOM, MUC1, MUC4, MYC, NRXN3, PAX5, PTPN1, SEMA6A, SPARC, SPATS2L, SPRED1, TAL1, TP53INP1, WT1