HopeSeq Heme Mutations Comprehensive

A next generation sequencing (NGS) based assay designed to target the entire coding sequence of commonly mutated genes in hematologic malignancies.

HopeSeq HemeMutations Gene List

Full-length mutation analysis of 135 genes:

ABL1, ARID1A, ASXL1, ATM, B2M, BCL2, BCL6, BCOR, BCORL1, BIRC3, BRAF, BTK, CALR, CARD11, CBL, CBLB, CCND1, CCND3, CD38, CD3E, CD3G, CD79A, CD79B, CDK4, CDK7, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CEBPA, CHD2, CRBN, CREBBP, CSF3R, CUX1, CXCR4, DDx3x, DIS3, DNMT3A, E2F1, EGFR, EP300, ETV6, EZH2, FBXW7, FGFR3 , FH, FLT3, FAM46C, FOXO1, GATA1, GATA2, GNA13, GNAS, HCK, HRAS, ID3, IDH1, IDH2, IGLL5, IKZF1, IL6, IL7R IRF4, JAK1, JAK2, JAK3, KDM6A, KIT, KMT2A, KMT2C, KMT2D, KRAS, LCK, LMO2, MAPK1, MEF2B, MGA, MIR142, MPL, MYC, MYD88, NFKB2, NOTCH1, NOTCH2, NPM1, NRAS, NTRK1, PAX5, PDCD1, PDGFRA, PHF6, PIGA, PIK3CA, PIK3CD, PIK3CG, PIK3R5, PLCG2, POT1, PRDM1, PTEN, PTK2B, PTPN11, RAD21, RB1, RFC4, RPS15, RUNX1, SETBP1, SF3B1, SMC1A, SMC3, SOCS1, SOCS6, SPI1, SRSF2, STAG2, STAT3, STAT5A, STAT5B, STAT6, SUZ12, TCF3, TET2, TNFAIP3, TP53, TP63, U2AF1, UBR5, WHSC1, WHSC1L1, WT1, XPO1, ZEB1, ZRSR2

 

Specimen Requirements - Molecular Oncology