Current Nesvig Research Projects

LYMPHOMA RESEARCH PROJECTS FUNDED FOR 2011
 
PI Name & Department
Division and Project Title
 
 
 
Ravi Bhatia, MD
Hematopoietic Stem Cell & Leukemia
 
Gene expression abnormalities in hematopoietic cells from lymphoma patients at risk for t-MDS (Renewal Application)
 
 
 
 
 
Smita Bhatia, MD
Population Sciences
 
 
Constitutional short telomeres as genetic susceptibility markers for adverse events in patients undergoing autologous HCT for lymphoma (Renewal Application)
 
 
 
David Horne, PhD
Sangkil Nam, PhD
Molecular Medicine
 
Development of a First-In-Class dual EGFR/Microtubule Small Molecule Inhibitor for the Treatment of Lymphoma
 
 
 
Wendong Huang, PhD
Gene Regulation & Drug Discovery
Targeting lymphoma by a natural compound
 
 
 
 
 
Markus Kalkum, PhD
Immunology
 
An antifungal Vaccine to Improve the Survival of Patients Treated for Lymphomas and other Hematologic Malignancies
 
 
 
Amrita Krishnan, MD
John Zaia, MD
Hem/HCT
Molecular, Immunologic and Viral analyses of AIDS related non Hodgkin Lymphoma
 
 
 
 
Takahiro Maeda, PhD
Hematopoietic Stem Cell & Leukemia
Signature-based small molecule screening for Non-Hodgkin Lymphoma (Renewal Application)
 
 
 
 
Sophia Wang, PhD
Leslie Bernstein, PhD
Larry Weiss, MD
Etiology
Molecular and genetic determinants of NHL survival (Renewal Application)
 
 
 
 
 
Sophia Wang, PhD
Leslie Bernstein, MD
James Lacey
Stephen J. Forman, MD
Rebecca Nelson
Etiology
Etiologic role of implants in T-cell Lymphomas (Renewal Application)
 
 
 
 
 
 
John Zaia, MD
Auayporn Nademanee, MD
Amrita Krishnan, MD
Virology
Co-stimulatory molecule profile in B-cell Lymphoma subjects undergoing auto and allo-HCT (Renewal Application)
 
 
 
 
 
Chih-Pin Liu, PhD
Immunology
Molecular regulation of T lymphoma cell death  (Renewal Application)
 
 
 
Yuan Chen, PhD
Molecular Medicine
 
Metabolomic biomarkers associated with the Development of T-MDS
 
 
 
 
Yun Yen, MD
Lufen Chang, PhD
Clinical & Molecular Pharmacology
 
Targeting TNFa/IKKb/NF-kB canonical pathway for the treatment of MCL
 
 
 
 
 
 
Garrett Larson, PhD
Ryotaro Nakamura, MD
Molecular Medicine
 
Influence of genomic structural variants on GVHD and Relapse Risk in Lymphoma Patients Treated with Allogeneic HSCT (Renewal Application)
 
 
 
 
Robert Chen, MD
Hem/HCT
 
Developing an in vivo model of siRNA therapy in mantle cell lymphoma
 
 
 
 
Xiuli Wang, PhD
Hem/HCT
 
 
Platform development for deriving CD19 specific central memory T cells for clinical trials  (Renewal Application)
 
 
 
 
Defu Zeng, MD
Diabetes, Endocrinology & Metabolism
 
Separation of graft versus lymphoma from graft versus host disease via anti-CD3-based conditioning  (Renewal Application)
 
 
 
 
David Ann, PhD
Mei Kong, PhD
Molecular Pharmacology
 
Targeting metaboloc pathways for B lymphoma therapy
 
 
 
 
 
Batia Avni, MD
Cancer Immunotherapeutics & Tumor Immunology
 
Combination of anti-CD-20-IL2 Immunocytokine and Lenalidomide for the enhancement of NK Cells in Human Lymphoma Bearing SCID Xenograft Model
 
 
 
 
Batia Avni, MD
Cancer Immunotherapeutics & Tumor Immunology
 
Defining the presence and content of tumor derived exosomes in the peripheral circulation of patients with b cell non Hodgkin lymphomas
 
 
 
 
 
David Colcher, PhD
Cancer Immunotherapeutics & Tumor Immunology
 
 
Preparation of an anti-CD25 antibody Conjugate for Phase I/II Studies of Autologous Hematopoietic Cell Transplant in Conjuction with BEAM Conditioning for Patients with CD25+ Hodgkin or T-cell non-Hodgkin Lymphomas
 
 
 
 
Don Diamond, PhD 
Virology
 
 
Optimizing shRNA Approaches for control of Experimental Murine Lymphoma using Salmonella Delivery Systems
 
 
 
 
Maciej Kujawski, PhD
Christine Brown, PhD
Cancer Immunotherapeutics & Tumor Immunology
 
Blocking Stat3 signaling in lymphoma-specific CD8+ T cells to improve their anti-tumor responses
 
 
 
 
 
 
Wendy Landier, PhD, RN
Smita Bhatia, MD
Population Sciences
 
Quadrivalent Human Papillomavirus (HPV) Vaccine in Lymphoma Survivors
 
 
 
 
 
Heehyoung Lee, PhD
Cancer Immunotherapeutics & Tumor Immunology
 
Targeting S1P/S1PR1-STAT3 signaling pathway: novel therapeutic strategy for diffuse large B cell lymphoma
 
 
 
 
Ren-Jang Lin, PhD
Molecular & Cellular Biology
 
Post-transcriptional deregulation of oncogenic microRNAs in lymphoma
 
 
 
 
 
V.N. Ngo, PhD
Hematopoietic Stem Cell & Leukemia
 
Functional Genetic Screen for Novel Molecular Targets in Mantle Cell Lymphoma
 
 
 
 
 
Tim O'Connor, PhD 
Res-Biology
 
Exploiting DNA Repair Defects in Hodgkin Lymphoma
 
 
 
 
 
Can-Lan Sun, PhD
Population Sciences
 
 
Urinary Tea Polyphenols an dLymphoma:  the Singapore Chinese Health Study and Shanghai Cohort Study
 
 
 
 
Zuoming Sun, PhD
Immunology
 
Interplay between inflammation and glycolysis in lymphoma
 
 
 
John Williams, PhD
Molecular Medicine
 
 
Tumor activated Procalins: CTLA-4 antagonists to treat lymphoma
 
 
 
 
 
John Williams, PhD
David Colcher, PhD
Andrew Raubitschek, MD
Molecular Medicine
 
Development of a synergistic anti-CD20 mAb / holetope-Fc combination for enhanced treatment of lymphoma
 
 
 
 
 
 
Defu Zeng, PhD 
Diabetes, Endocrinology & Metabolism
 
BAFF-R Aptamer-SiRNA Chimeras for prevention and Treatment of Chronic GVHD and Lymphoma Relapse in HCT Recipients