Our students have made real and lasting contributions to help advance biomedical knowledge. Some summer students become co-authors on papers, not only giving them the thrill of seeing their name in print, but giving them a great addition to their CV for future educational and career pursuits. Several of our high school students have submitted their projects to the Westinghouse Science Talent Search and have won scholarships. Previous CURE students have won travel awards to present their summer research projects at the Annual Biomedical Research Conference for Minority Students (ABRCMS). Sometimes the work even translates into valuable intellectual property such as inventions.
, summer student in 2012 and 2016. Loss of the Polycomb mark from bivalent promoters leads to activation of cancer-promoting genes in colorectal tumors
. Hahn, M., Li, A., Wu, X., Yang, R.
, Drew, D., Rosenberg, D., Pfeifer, G. (2014). Cancer Res. 2014 Jul 1; 74(13): 3617–3629PMCID: PMC4079738
Tiankun Kevin Wang
, summer student in 2014, 2015. Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into cells in mice with reversal of diabetes
. Zhang, M., Lin, Q., Qi, Tong., Wang, TK.
, Chen, C., Riggs, A., Zeng, D. PNAS. January 2016.
, summer student in 2013, 2014 and Jose Ortiz
, summer student in 2012, 2013. Human Cytomegalovirus Vaccine Based on the Envelope gH/gL Pentamer Complex
. Wussow F, Chiuppesi F, Martinez J, Flechsig C, Campo J, Newell M, Tran E, Ortiz
J, La Rosa C, Longmate J, Barry PA, Diamond DJ. Plos Pathogens, DOI: 10.1371/journal.ppat.1004524.
, summer student in 2011. Shannon Owens
, summer student in 2012, 2013. Alleles of the homologous recombination gene, RAD59, identify multiple responses to disrupted DNA replication in Saccharomyces cerevisiae
. Liddell, L. C., Manthey, G. M., Owens, S. N., Fu, B. X. H
., and A. M. Bailis. BMC Microbiol. 2013; 13:229 PMID:24125552
, summer student in 2012. Altered expression of Polycomb group genes in glioblastoma multiforme
. Li, G., Warden, C., Zhaoxia, Z., Neman, J., Jain, A.
, Jandial, R., Chen, M. Plos One 2013 8(11):e80980
, summer student in 2012, 2013. Systemic Delivery of Salmonella Typhimurium Transformed with IDO shRNA Enhances Intratumoral Vector Colonization and Suppresses Tumor Growth. Blache CA, Manuel ER, Kaltcheva TI, Wong AN
, Ellenhorn JDI, Blazar BR, and Diamond DJ. Cancer Res. 2012; 72:6447-6456. PMC3525777
, summer student in 2012. MHC-mismatched chimerism is required for induction of transplantation tolerance in autoimmune nonobese diabetic recipients
. Wang, M, Racine, J, Zhang, M, Wu, T, Deng, R, Johnston, H, Shen, C, Siswanto, K
, Zeng, D. J Immunol. 2014;193(4):2005-15
, summer student in 2011. Sequential Posttranslational Modifications Program FEN1 Degradation during Cell-Cycle Progression
. Guo Z, Kanjanapangka J, Liu N, Liu S, Liu C, Wu Z, Wang Y, Loh T
, Kowolik C, Jamsen J, Zhou M, Truong K, Chen Y, Zheng L, Shen B. Molecular Cell 10;47(3):444-56. Epub 2012 Jun 30.
, summer student in 2010 and 2011. Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes
. Wang M, Racine JJ, Song X, Li X, Nair I, Liu H, Avakian-Mansoorian A, Johnston HF, Liu C, Shen C
, Atkinson M, Todorov I, Kandeel F, Forman S, Wilson B, Zeng D. Science Translational Medicine. 2012 May 9;4(133):133ra59.
, summer student in 2011 and 2012. Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease
Li X, Deng R, He W, Liu C, Wang M, Young J, Meng Z, Du C
, Huang W, Chen L, Chen Y, Martin P, Forman S, Zeng D. The Journal of Immunology. 2012 Jan 15;188(2):724-34. Epub 2011 Dec 12.
, summer student in 2011. miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
. Sun G, Ye P, Murai K, Lang MF, Li S, Zhang H, Li W, Fu C, Yin J, Wang A
, Ma X, Shi Y. Nat Commun. 2011 Nov 8;2:529.