Steven Rosen

Steven T. Rosen, M.D.

  • Irell & Manella Cancer Center Director’s Distinguished Chair
  • Morgan & Helen Chu Director’s Chair of the Beckman Research Institute
  • Provost and Chief Scientific Officer
  • Director, Comprehensive Cancer Center
  • Director, Beckman Research Institute
  • Director, Irell & Manella Graduate School of Biological Sciences
  • Professor, Department of Hematology & Hematopoietic Cell Transplantation
  • Hematologist/Oncologist

Steven T. Rosen, M.D.

Enfoque de la investigación :
  • Leukemia
  • Lymphoma
  • Multiple Myeloma
Especialidades clínicas
  • Hematology/Oncology

Steven T. Rosen, M.D., is provost and chief scientific officer for City of Hope and a member of City of Hope's Executive Team. He also is director of the comprehensive cancer center, Beckman Research Institute of City of Hope and the Irell & Manella Graduate School of Biological Sciences, holds the Irell & Manella Cancer Center Director's Distinguished Chair and the Morgan & Helen Chu Director’s Chair of the Beckman Research Institute.

Dr. Rosen sets the scientific direction of City of Hope, shaping the research and educational vision for the biomedical research, treatment and education institution. Working closely and collaboratively with City of Hope's scientists, clinicians and administrative leaders, he develops strategies that contribute to the organization's mission.

As director of BRI, he works with faculty across the institution to help shape and direct the scientific vision for BRI while leading the vital basic and translational research that is fundamental to our strategic plan and mission. He focuses on opportunities for expanding and integrating our research initiatives; recruiting and leading talented scientists; helping our talented researchers achieve national and international recognition; and promoting our national standing as a premier scientific organization.

Prior to joining City of Hope, Dr. Rosen was the Genevieve Teuton Professor of Medicine at the Feinberg School of Medicine at Northwestern University in Chicago. He served for 24 years as director of Northwestern's Robert H. Lurie Comprehensive Cancer Center. Under his leadership, the center received continuous National Cancer Institute (NCI) funding beginning in 1993 and built nationally recognized programs in laboratory sciences, clinical investigations, translational research and cancer prevention and control. The center attained comprehensive status in 1997.

Dr. Rosen has published more than 400 original reports, editorials, books and book chapters. His research has been funded by the National Cancer Institute, American Cancer Society, Leukemia & Lymphoma Society of America and Multiple Myeloma Research Foundation.Dr. Rosen also has served as an adviser for several of these organizations and on the external advisory boards of more than a dozen NCI-designated Comprehensive Cancer Centers. He is the current editor-in-chief of the textbook series "Cancer Treatment & Research."

Recognized as one of the Best Doctors in America, Dr. Rosen is a recipient of the Martin Luther King Humanitarian Award from Northwestern Memorial Hospital and the Man of Distinction Award from the Israel Cancer Research Fund. He earned his bachelor's degree and medical degree with distinction from Northwestern University, and is a member of the Alpha Omega Alpha Honor Society.
 

  • 2018-present, Morgan & Helen Director’s Chair of the Beckman Research Institute, City of Hope, Duarte, CA
  • 2014-present, Provost and Chief Scientific Officer, City of Hope, Duarte, CA
  • 2014-present, Director, Comprehensive Cancer Center, Beckman Research Institute and Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA
  • 1989-2014, Director, The Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL
  • 1989-2014, Director of Cancer Programs Northwestern Memorial Hospital, Chicago, IL
  • 1989-2014, Genevieve Teuton Professor of Medicine, Feinberg School of Medicine at Northwestern University, Chicago, IL
  • 1981-2014, Attending Physician Northwestern Memorial Hospital, Chicago, IL
  • 1982-1986 Assistant Professor, Department of Medicine, Northwestern Univ. Medical School, Chicago, IL
  • 1981-1987, Staff Physician, Division of Hematology/Oncology, Veterans Administration Lakeside Medical Center, Chicago, IL
  • 1981, Associate, Department of Medicine, Northwestern Univ. Medical School, Chicago, IL

Títulos

  • 1976, M.D., Northwestern University Medical School, Chicago, IL
  • 1972, B.M., Honors Program, Northwestern University, Evanston, IL

Beca de investigación

  • 1979-1981, Fellowship in Hematology/Oncology, National Cancer Institute, Bethesda, MD

Residencia

  • 1977-1979, Residency in Internal Medicine, Northwestern Memorial Hospital, Chicago, IL
Dr. Rosen is a clinician and scientist with expertise in the diagnosis and treatment of blood cancers, particularly Non-Hodgkin lymphoma, cutaneous lymphoma, chronic lymphocytic leukemia (CLL) and multiple myeloma. He has been a pioneer in the use of biological therapies including:
 
  • monoclonal antibodies and recombinant toxins that can specifically target cancer cells
  • apoptosis inducers, proteasome inhibitors and metabolism inhibitors to promote cancer cell death
  • RNA based analogs and cell signaling regulators that can interfere with cancer growth processes
  • vaccines, interferons and cytokines that can trigger an immune response against cancer cells
  • angiogenesis inhibitors to prevent cancer from growing new blood vessels
  • transcriptional regulators and antisense compounds to activate or silence certain genes in cancer and normal cells
  • hormone therapies
     
He has conducted numerous clinical trials and is recognized as one of the leading figures in “bench to bedside” research by rapidly transforming scientific breakthroughs into promising therapies.
 
Active
 
P30 CA033572 (Rosen)  12/01/12 - 11/30/17
NIH/NCI
Cancer Center Support Grant
The Cancer Center Support Grant provides support for administration and infrastructure for the City of Hope comprehensive Cancer Center.  Dr. Rosen is the Cancer Center Director.  The goals of the Cancer Center Support Grant are to conduct and support cancer research and to coordinate and integrate cancer–related activities of the institution, including community outreach initiatives; to develop and conduct cancer education programs; to promote and participate in state-of-the-art care of cancer center patients at the City of Hope and implement the initiatives in cancer prevention and control research.  These goals are accomplished through the activities of the 5 established programs and 10 shared resources
 
U54 CA151880-04 (Mirkin/Rosen) 09/21/10 - 07/31/15
NIH/NCI
Nanomaterials for Cancer Diagnostics and Therapeutics

The Northwestern University Center for Cancer Nanotechnology Excellence (NU-CCNE) will draw upon NU’s outstanding research strengths in the areas of cancer research, nanoscience, bioimaging and nano-tool development. The long-term objective of the NU-CCNE is to design and test nanomaterials and nanodevices for application in the clinic, ultimately facilitating the translation of novel and innovative nanoscale technologies that significantly improve cancer prevention, detection, diagnosis, and treatment.
Ralf Buettner
Staff Scientist
 
Xu Hannon Zhang
Assistant Research Professor
Ir al Inicio