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Ben Shih, Ph.D.

  • Assistant professor, Translational Research & Cellular Therapeutics

Ben Shih, Ph.D.

  • 2015 to present - Assistant Professor, Department of Translational Research & Cellular Therapeutics, Diabetes & Metabolism Research Institute at City of Hope, Duarte, CA
  • 2012 to 2015 - Research scientist, Sanford Consortium for Regenerative Medicine, University of California, San Diego, San Diego, CA 2001 to 2002 - Research assistant, National Taiwan University, Taipei, Taiwan

Títulos

  • 2007 - Oregon State University, Corvallis, OR, Ph.D. in Biochemistry and Biophysics
  • 1999 - National Taiwan University, Taipei, Taiwan, M.S. in Biochemistry and Molecular Biology
  • 1997 - National Taiwan University, Taipei, Taiwan, B.S. in Agriculture Chemistry

Beca de investigación

  • 2007 to 2012 - Post-doctoral fellow, Sanford Consortium for Regenerative Medicine, University of California, San Diego, San Diego, CA
  • 2002 to 2007 - Pre-doctoral fellow, Oregon State University, Corvallis, OR
  • Shih H.P. and Sander M. Embryonic pancreas explant culture systems. (2014) Methods in Stem Cell and Tissue Repair ). 1210:229-37
  • Rockich B.E., Hrycaj S.M., Shih, H.P., Nagy M.S., Ferguson, M.A., Kopp, J.L., Sander M.S., Wellik D.M., Spence, J.R. Sox9 plays multiple roles in the lung epithelium during branching morphogenesis (2013) Proc Natl Acad Sci. 110:E4456-64
  • Shih H.P.*, Wang A.*, Sander M., Pancreas Organogenesis: From Lineage Determination to Morphogenesis (2013) Annual Review of Cell and Developmental Biology, 29: 19.1-25 (*contributed equally) Times cited: 7
  • Jin L., Feng T., Shih H.P., Zerda R., Luo A., Hsu J., Mahdavi A., Sander M., Tirrell D.A., Riggs A.D., Ku H.T. Colony Forming Cells in the Adult Mouse Pancreas are Expandable in Matrigel and Form Endocrine/acinar Colonies in Laminin Hydrogel (2013) Proc Natl Acad Sci. 110:3907-12
  • Seymour P.A., Shih H.P., Patel N.A., Freude K.K., Xie R., Lim C.J., Sander M. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. (2012) Development 139:3363-72.
  • Shih H.P., Kopp J.L., Sandhu M., Dubois C.L., Seymour P.A., Grapin-Botton A., Sander M. A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. (2012) Development 139:2488-99. Times cited: 27 (including 8 review articles)
  • Eng D., Ma H.Y., Xu J., Shih H.P., Gross M.K., Kiouss C. Loss of abdominal muscle in pitx2 mutants associated with altered axial specification of lateral plate mesoderm. (2012) PLoS One. 7:e42228
  • Campbell A.L., Shih H.P., Xu J., Gross M.K., Kioussi C. Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2. (2012) PLoS One. 7:e35822.
  • Kopp J.L., Dubois C.L., Schaffer A.E., Hao E., Shih H.P., Seymour P.A., Ma J., Sander M. Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. (2011) Development 138:653-65.
  • Shih H.P.*, Dubois C.L.*, Seymour P.A., Patel N.A., Behrmann J.M., Ngo V., Sander M. Sox9-haploinsufficiency causes glucose intolerance in mice. (2011) PLoS One. 6:e23131. (*contributed equally) Times cited: 14
  • Seymour P.A., Freude K.K., Dubois C.L., Shih H.P., Patel N.A., Sander M. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. (2008) Developmental Biology 323:19-30.
  • Jonckheere, N., Mayes, E., Shih, H.P., Li, B., Lioubinski, O., Dai, X., Sander, M. Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation. (2008) Developmental Biology 318:224-35.
  • Shih H.P., Gross M.K., Kioussi C. Forming the Head Muscles. (2007) Acta Histochemica 110:97-108. Times cited: 31
  • Shih H.P., Gross M.K., Kioussi C. Cranial Muscle Defects of Pitx2 Mutants Result from Specification Defects in the First Branchial Arch. (2007) Proc Natl Acad Sci. 104:5907-12. Times cited: 65
  • Shih H.P., Gross M.K., Kioussi C. Expression pattern of the homeodomain transcription factor Pitx2 during muscle development. (2007) Gene Expr Patterns. 7:441-51. Times cited: 37
  • Kioussi C., Shih H.P., Loflin J., Gross M.K. Prediction of active nodes in the transcriptional network of neural tube patterning. (2006) Proc Natl Acad Sci. 103:18621-6.
  • 2014 - Beta Cell Biology Consortium Investigator Retreat Scholarship Award
  • 2012 - Keystone Symposia Scholarship Award, Advances in Islet Biology
  • 2009 to 2011 - JDRF Post-doctoral fellowship award
  • 2007 - Student Presentation Award, Society for Developmental Biology, Annual Northwest Meeting
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