An NCI-designated Comprehensive Cancer Center

Bart O. Roep, Ph.D.

Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes
Research Focus
  • Type 1 diabetes
  • Immunology
  • Immunotherapy
  • Gene therapy
Professor and Chair, Department of Diabetes Immunology

Bart O. Roep, Ph.D., is Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes and the founding chair of the Department of Diabetes Immunology within City of Hope's Diabetes & Metabolism Research Institute. He is an internationally recognized authority and key opinion leader on multiple aspects of type 1 diabetes, with particular interest in understanding the cause of the disease and translating this knowledge into immune intervention strategies (including gene therapy, stem cell therapy and bone marrow transportation) with the ultimate goal to cure type 1 diabetes.

Dr. Roep’s mission is to cure people from type 1 diabetes. His quest of over 25 years has been honored with multiple scientific and medical awards, including the most prestigious national and European awards in diabetes such as the Minkowski Prize for outstanding contributions to the advancement of knowledge in the field of diabetes mellitus.

Highlights of Dr. Roeps' career include discovering which targets in insulin-producing beta-cells are recognized by self-destructive T cells, which can be translated into immune-based therapies targeting this mechanism. He is also the first to discover immune system factors that predicts clinical outcome of islet transplantation for type 1 diabetic islet recipients, setting the stage for personalized medicine.

Dr. Roep received his medical and doctorate degrees at Leiden University in the Netherlands and his Master of Science degree at the University of Amsterdam.


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

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Research led by City of Hope’s Bart O. Roep, Ph.D., advances personalized medicine for children with type 1 diabetes