Jianhuang Xue, Ph.D.

626-218-5628

Postdoctoral Fellow

Research Area

Targeted Therapy for Leukemia

Mechanisms and Regulations of RNA Modification

Education & Experience

Degrees

2012-2018. Ph.D., Biochemistry and Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China
2008-2012, B.S., Biochemistry, School of Life Sciences, Nanjing University, Nanjing, China

Professional Experience

2019-Present, Postdoctoral Fellow, Beckman Research Institute of City of Hope, Monrovia, CA
2019, Research Associate, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China

Awards & Memberships

Awards

2019, Ray Wu Prize
2019, Excellent Graduate in Beijing
2019, Excellent Graduate of University of Chinese Academy of Sciences
2018, National Scholarship, Ministry of Education of the People's Republic of China
2016, Merit Student, University of Chinese Academy of Sciences
2012, Outstanding Graduate of Nanjing University

Publications

Xue JH, Chen GD, Hao F, Chen H, Fang Z, Chen FF, Pang B, Yang QL, Wei X, Fan QQ, Xin C, Zhao J, Deng X, Wang BA, Zhang XJ, Chu Y, Tang H, Yin H, Ma W, Chen L, Ding J, Weinhold E, Kohli RM, Liu W, Zhu ZJ, Huang K, Tang H, Xu GL. A vitamin-C-derived DNA modification catalysed by an algal TET homologue Nature 569, 581-585, (2019).

Xue JH, Xu GF, Gu TP, Chen GD, Han BB, Xu ZM, Bjørås M, Krokan HE, Xu GL, Du YR. Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation J. Biol. Chem. 2016, 291:731-738.

Xue JH, Xu GL. RNA Pol II as a sensor of 5caC Cell Research (2015) 25:1089-1090.

Dou X, Boyd-Kirkup JD, McDermott J, Zhang X, Li F, Rong B, Zhang R, Miao B, Chen P, Cheng H, Xue J, Bennett D, Wong J, Lan F, Han JJ. The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A. Genome Research 2019 29(10):1622-1634.