Lauren VanderSpek

Lauren A. Lukas Vanderspek, M.D.

  • Assistant Clinical Professor, Department of Radiation Oncology
  • Radiation Oncologist

Lauren A. Lukas Vanderspek, M.D.

Clinical Specialties
  • Radiation Oncology
Areas of Expertise
  • Brain Tumors
  • Primary and Metastatic Central Nervous System
  • Hepatobiliary, Gastrointestinal, Lung, Gynecologic and Breast Cancers
Lauren A. Lukas VanderSpek, M.D., is a board-certified radiation oncologist who's spent the past decade treating patients in Mission Hills and throughout the San Fernando Valley of Los Angeles.

Dr. VanderSpek is an honors graduate of the University of Western Ontario and the University of Toronto, where she received her medical degree.

Dr. VanderSpek is well-versed in all forms of radiation therapy, including stereotactic radiosurgery, stereotactic body radiotherapy, brachytherapy, Y-90, and Xofigo.
  • 2018 - present, Assistant Professor, Department of Radiation Oncology, Radiation Oncologist, City of Hope, Duarte, CA
  • 2009 - 2018, Radiation Oncologist and Medical Director, Valley Radiotherapy Associates, Mission Hills, CA

Mission Hills Radiation Oncology

City of Hope Mission Hills Radiation Oncology, 15031 Rinaldi St., Mission Hills, CA, 91345

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Phone :  818-496-4410


  • 2004, M.D. with honors, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
  • 2000, B.S. Scholar's Electives - Biophysics with distinction, The University of Western Ontario, London, Ontario, Canada


  • 2004 - 2009, Resident, Department of Radiation Oncology, Faculty of Medicine and Dentistry, The University of Western Ontario, Ontario, Canada
T.P. Yeung, S. Yartsev, T.Y. Lee, E. Wong, W. He, B. Fisher, L. VanderSpek, D. Macdonald, G. Bauman. Relationship of computed tomography perfusion and positron emission tomography to tumor progression in malignant glioma. J Med Radiat Sci. 2014 Feb; 61(1):4-13
A.Hallock, K. Surry, D. Batchelar, L. VanderSpek, J. Yuen, A. Hammond, J. Radwan, B. Yaremko, G. Rodrigues, D. D’Souza. An early report on outcomes after CT based HDR brachytherapy for locally advanced cervix cancer: a single institution experience. Practical Radiation Oncology. 2011 Jul-Sep; 1(3):173-81.

S.K. Nath, J.D. Lawson, D.R. Simpson, L. VanderSpek, J.Z. Wang, J.F. Alksne, J, Ciacci, A.J. Mundt, K.T. Murphy, Single-isocenter frameless intensity-modulated stereotactic radiosurgery for simultaneous treatment of multiple brain metastases: clinical experience.  Int J of Radiat Oncol Biol Phys. 2010 Sep 1;78(1):91-7.
L. VanderSpek, G. Bauman, J.Z, Wang, S. Yartsev, C. Menard, Y.B. Cho, A.J. Mundt, J.D. Lawson, K.T. Murphy.  Dosimetric comparison of Intensity-Modulated Radiosurgery and Helical Tomotherapy for the treatment of multiple intracranial metastases.  Technology in Cancer Research and Treatment. 2009;8:361-368.
L. VanderSpek, B. Fisher, G. Bauman, D. Macdonald. 3D Conformal Radiotherapy and Cisplatin for Recurrent Malignant Glioma. Can. J. Neurol. Sci. 2008; 35: 57-64
LA Lukas VanderSpek, GR Pond, W Wells, RW Tsang. Radiation therapy for Bowen’s disease of the skin. Int J of Radiat Oncol Biol Phys. 2005 Oct 1:63 (2): 505-10.
LA Lukas, KJM Surry, TM Peters. Temperature dosimetry using MR relaxation characteristics of poly(vinyl alcohol) cryogel (PVA-C). Magnetic Resonance in Medicine. 46:1006-1013, Nov. 2001.
  • American Society for Therapeutic Radiology and Oncology
  • American College of Radiology
  • American Medical Association
  • California Medical Association
  • Fellow of the Royal College of Physicians and Surgeons of Canada
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