Lei Gao, Ph.D.

626-218-5628
Lei Gao - Systems Biology
Postdoctoral Fellow
Research Area
Generation of transgenic mice
Mechanism of tumorigenesis
Lei Gao received his Ph.D. degree from Beijing Normal University in Biochemistry and Molecular Biology. During his studies, he received training for transgenic mice generation and generated cl-tTA transgenic mice with a technology called functionally enriched ES cell transgenics (FEEST), which is a highly efficient technique used to guarantee expression of the gene of interest. While doing cancer research, he found that GATA4 functioned as a tumor suppressor gene in lung cancer. His current project is focused on the study of RNA modification in cancer.
Education & Experience
Degrees

  • 2018, Ph.D., Beijing Normal University, China, School of Life Sciences

  • 2013, M.S., Beijing, College of Animal Science & Technology, University of Agriculture, China

    2010, B.S. , Yangzhou University, China, College of Veterinary medicine

Professional Experience

  • 2019-2021, Postdoctoral Fellow, Department of Systems Biology, City of Hope, Monrovia, CA

  • 2018, Postdoctoral Fellow, Department of Pathology & Genomic Medicine, Methodist Hospital, Houston, Texas

Awards & Memberships
Awards

  • 2016-2017, First Prize Scholarship, Beijing Normal University

  • 2015-2016, National Scholarship, Beijing Normal University

Publications
  • Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, Zhang A, Tang N, Chen T, Luo M, Yu L, Gao S, Chen L. Efficient Generation of Mice with Consistent Transgene Expression by FEEST, Sci Rep. 2015, 5:16284; doi: 10.1038/srep16284
  • Xu N, Fang W, Mu L, Tang Y, Gao L, Ren S, Cao D, Zhou L, Zhang A, Liu D, Zhou C, Wong K, Yu L, Zhang L, Chen L, Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer. Oncotarget, 2015 Dec 4. doi: 10.18632/oncotarget.6461