An NCI-designated Comprehensive Cancer Center
Mingye Feng

Mingye Feng, Ph.D.

Assistant Professor, Department of Immuno-Oncology
Research Focus
  • Macrophage-mediated immunosurveillance

Research Teams


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

Zhu F*, Feng M*, Sinha R, Murphy MP, Luo F, Kao KS, Szade K, Seita J, and Weissman IL. The GABA receptor GABRR1 is expressed on and functional in hematopoietic stem cells and megakaryocyte progenitors. Proc Natl Acad Sci USA. 2019 Sep 10; 116(37):18416-18422. (*equal contribution). PMID: 31451629.
Feng M*#, Jiang W*#, Kim BY, Zhang C, Fu YX, and Weissman IL. Phagocytosis checkpoints as new targets for cancer immunotherapy. Nat Rev Cancer. 2019 Oct; 19(10):568-586. (*equal contribution, #co-corresponding author). PMID: 31462760.
Zhu F, Feng M, Rahul S, Seita J, Mori Y, and Weissman IL. Screening for genes that regulate the differentiation of human megakaryocytic lineage cells. Proc Natl Acad Sci USA 2018 Aug 27.
Folkes AS, Feng M, Zain JM, Abdulla F, Rosen ST, and Querfeld C. Targeting CD47 as a cancer therapeutic stragety: the cutaneous T-cell lymphoma experience. Curr Opin Oncol. 2018 Sep; 30 (5): 332-337.
Feng M*, Marjon KD*, Zhu F*, Weissman-Tsukamoto R*, Levett A, Sullivan K, Kao KS, Markovic M, Bump PA, Jackson HM, Choi TS, Chen J, Banuelos AM, Liu J, Gip P, Cheng L, Wang D, and Weissman IL#. Programmed cell removal by calreticulin in tissue homeostasis and cancer. Nat Commun 2018 Aug 10; 9 (1): 3194. (*equal contribution, #co-corresponding author).
Weiskopf K, Schnorr PJ, Pang WW, Chao MP, Chhabra A, Seita J, Feng M, and Weissman IL. Myeloid Cell Origins, Differentiation, and Clinical Implications. Microbiol Spectr 2016 Oct; 4 (5).
Feng M, Chen JY, Weissman-Tsukamoto R, Volkmer JP, Ho PY, McKenna KM, Cheshier S, Zhang M, Guo N, Gip P, Mitra SS, and Weissman IL. Macrophages eat cancer cell using their own calreticulin as a guide: roles of TLR and Btk. Proc Natl Acad Sci USA 2015 Feb 17; 112 (7): 2145-50.
Leitch S*, Feng M*, Muend S, Braiterman LT, Hubbard AL, and Rao R. Vesicular distribution of Secretory Pathway Ca2+-ATPase isoform1 (SPCA1) and a role in manganese detoxification in liver-derived polarized cells. Biometals 2011 Feb; 24 (1): 159-70. (*equal contribution)
Feng M, Grice DM, Faddy HM, Nguyen N, Leitch S, Wang Y, Muend S, Kenny PA, Sukumar S, Roberts-Thomson SJ, Monteith GR, and Rao R. Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell 2010 Oct 1; 143 (1): 84-98.
Faddy HM, Smart CE, Xu R, Lee GY, Kenny PA, Feng M, Rao R, Brown MA, Bissell MJ, Roberts-Thomson SJ, and Monteith GR. Localization of plasma membrane and secretory calcium pumps in the mammary gland. Biochem Biophys Res Commun 2008 May 9; 369 (3): 977-81.
Xiang M, Feng M, Muend S, and Rao R. A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension. Proc Natl Acad Sci USA 2007 Nov 20; 104 (47): 18677-81.
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