An NCI-designated Comprehensive Cancer Center
Gauri Deb

Gauri Deb, Ph.D.

Postdoctoral Fellow, Department of Systems Biology
Research Focus
  • Autoimmunity checkpoint (AIC) activation mechanisms
  • Targeting the autoimmunity associated PTPN22 phosphatase for AIC activation in B and T cell malignancies
  • Lgr5 as negative regulator of Wnt signaling in normal and transformed B cells
Email: [email protected]

Research Teams

  • Systems Biology

Igoe N, Bayle ED, Fedorov O, Tallant C, Savitsky P, Rogers C, Owen DR, Deb G, Somervaille TC, Andrews DM, Jones N, Cheasty A, Ryder H, Brennan PE, Müller S, Knapp S, Fish PV. Design of a biased potent small molecule inhibitor of the bromodomain and PHD finger-containing (BRPF) proteins suitable for cellular and in vivo studies. J Med Chem. 2017; 60:668-680.

Deb G, Somervaille TCP. Antagonizing self-renewal in acute myeloid leukemia: ID2 takes the stage. Cancer Cell 2016; 30:5-7.

Deb G, Thakur VS, Limaye AM, Gupta S. Epigenetic induction of tissue inhibitor of matrixmetalloproteinase-3 by green tea polyphenols in breast cancer cells. Mol Carcinog. 2015; 54: 485-499.

Deb G, Batra S, Limaye AM. Data in support of the negative influence of divalent cations on (-)-epigallocatechin-3-gallate (EGCG)-mediated inhibition of matrix metalloproteinase-2 (MMP-2). Data Brief. 2015; 6:461-465.

Sheeba JMDJ, Mohan CM, Hussain M, Deb G, Kumar N, Limaye AM. Estrogen-regulated extracellular matrix remodeling genes in MCF-7 breast cancer cells. Gene Rep. 2015; 3:14-21.

Deb G, Singh AK, Gupta S. EZH2: Not EZHY (easy) to deal. Mol Cancer Res. 2014; 12:639-653.

Deb G, Thakur VS, Gupta S. Multifaceted role of EZH2 in breast and prostate tumorigenesis: Epigenetics and beyond. Epigenetics 2013; 8:464-476.

Manjegowda MC, Deb G, Kumar N, Limaye AM. Expression profiling of genes modulated by estrogen, EGCG or both in MCF-7 breast cancer cells. Genom Data. 2015; 10: 210-212.

Thakur VS, Deb G, Babcook M, Gupta S. Plant phytochemicals as epigenetic modulators: Role in cancer chemoprevention. AAPS J. 2014; 16:151-163.

Manjegowda CM, Deb G, Limaye AM. Epigallocatechin -3-gallate induces steady state mRNA levels of PS2 and PR genes in MCF-7 breast cancer cells. Indian J Exp Biol. 2014; 52:312-316.

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