An NCI-designated Comprehensive Cancer Center
Jeannine McCune

Jeannine McCune, Pharm.D.

Professor, Department of Population Sciences and Department of Hematology & Hematopoietic Cell Transplantation
Clinical Expertise
  • Clinical Pharmacology
  • Pharmacokinetics
  • Ancillary Biomarker Studies
  • Grant Writing & Reviewing
  • Pediatrics
  • Hematopoietic Cell Transplant
Jeannine McCune, Pharm.D., has over 20 years of clinical research experience in oncology, predominantly in special populations — specifically hematopoietic cell transplant and pediatric cancer patients. She leads a multidiscliplinary team of analytic chemists, study coordinators and data managers to successfully conduct pharmacokinetic/dynamic studies in cancer patients.

Locations

City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

  • Navarro SL, Randolph TW, Shireman L, Raftery MD, McCune JS. Endogenous metabolites predict IV busulfan clearance in hematopo9etic cell transplant patients. J Proteome Res 2016 Aug 5;15(8):2802-11. DOI: 10.1021/acs.jproteome.6b00370. PMID:  27350098.
  • Palmer J, McCune JS, Perales M-A, Marks D, Bubalo J, Mohty M, Wingard JR, Paci A, Hassan M, Bredeson C, Pidala J, Shah N, Shaughnessy P, Majhail N, Schriber J, Savani BN, Carpenter PA. Personalizing Busulfan-based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee. *shared first authorship. Biol Blood Marrow Transplant. 2016 Nov;22(11):1915-1925. DOI: 10.1016/j.bbmt.2016.07.013. Epub 2016 Jul 29.  PMID:  27481448.
  • McDermott CL, Sandmaier BM, Storer B, Li H, Mager DE, Boeckh MJ, Bemer MJ, Knutson J, McCune JS. Non-relapse mortality and mycophenolic acid exposure in nonmyeloablative hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2013 Aug;19(8):1159-66. DOI: 10.1016/j.bbmt.2013.04.026. Epub 2013 May 6. PMID: 23660171.
  • McCune JS, Batchelder A, Guthrie KA, Witherspoon R, Appelbaum FR, Phillips B, Vicini P, Salinger DH, McDonald GB. Personalized Dosing of Cyclophosphamide in the Total Body Irradiation - Cyclophosphamide Conditioning Regimen: A Phase II Trial in Patients with Hematologic Malignancy. Clin Pharmacol Ther. 2009 Jun; 85 (6): 615-622. (epub 18 March 2009) (PMC 19295506, NIHMS111512). Results summarized in Reuters Health and Medscape Oncology, July 2009.
  • McCune JS, Salinger DH, Vicini P, Phillips B, Oglesby C, Park JR. Pharmacokinetics of Cyclophosphamide and Metabolites in Children with Neuroblastoma. J Clin Pharmacol. 2009 Jan;49(1):88-102. Epub 2008 Oct 16. (Pubmed Central (PMC) 2652687, NIHMS94095)
  • Woodahl EL, Hingorani SR, Wang J, Guthrie KA, McDonald GB, Batchelder A, Li M, Schoch HG, McCune JS. Pharmacogenomic Associations in ABCB1 and CYP3A5 With Acute Kidney Injury and Chronic Kidney Disease After Myeloablative Hematopoietic Cell Transplantation, Pharmacogenomics J. 2008 Aug;8(4):248-55. Epub 2007 Aug 14.
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